ReviewEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2010
A survey of metastatic central nervous system tumors to cervical lymph nodes.
Review in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Adult Primary Central Nervous System Atypical Teratoid/Rhabdoid Tumor Metastasizing to the Cervical Lymph Node.Cureus · 2024Article
- Cervical Lymph Node Metastasis From Medulloblastoma in a Young Adult: Case Report and Literature Review.Cureus · 2024Article
- Cervical Lymph Node Metastases from Central Nervous System Tumors: A Systematic Review.Cancer management and research · 2022Review
- Transportation of Single-Domain Antibodies through the Blood-Brain Barrier.Biomolecules · 2021Review
- CNS-Draining Meningeal Lymphatic Vasculature: Roles, Conundrums and Future Challenges.Frontiers in pharmacology · 2021Review
- Meningeal lymphatic vessels regulate brain tumor drainage and immunity.Cell research · 2020Article
- Metastatic Squamous Cell Carcinoma to the Cervical Lymph Nodes From an Unknown Primary Cancer: Management in the HPV Era.Frontiers in oncology · 2020Review
- Diagnostic and treatment modalities for patients with cervical lymph node metastases of unknown primary site - current status and challenges.Radiation oncology (London, England) · 2017Review
- The Microenvironmental Landscape of Brain Tumors.Cancer cell · 2017Review
- Cervical lymph node metastases from remote primary tumor sites.Head & neck · 2016Review
- New Brain Lymphatic Vessels Drain Old Concepts.EBioMedicine · 2015Review
- A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules.The Journal of experimental medicine · 2015Article
- Supratentorial extraventricular anaplastic ependymoma with extracranial metastasis.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2015Article
- Rare Cases of Extracranial Metastases from High-grade Glioma Detected on FET PET-CT with Histopathological Confirmation.Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, IndiaArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the realm of head and neck diseases, one particularly common clinical presentation is that of the patient with a cervical mass. In children, neck masses often prove to be developmental cysts; in adults, the recent onset of a neck mass can signal a metastasis from a head and neck squamous carcinoma. Less often, both adults and children may present with cervical masses caused by either non-Hodgkin's lymphoma or Hodgkin's disease. There are, of course, less frequently encountered differential diagnostic possibilities; one of the most uncommon of all is the possibility of metastasis from an intracranial tumor. Intracranial tumors rarely give rise to cervical node metastases. The present review examines the published experience with 128 tumors that gave rise to cervical node metastases in both adult and in pediatric patients. While it is presumed that the blood-brain barrier blocks the spread of most tumors beyond the intracranial locale, this is speculative. Although many of the cervical node metastases reported here arose after craniotomy (and, presumably, after breaching of the blood-brain barrier), some arose in the absence of any preceding surgical procedure. Cervical node metastases may arise from glial tumors (including glioblastoma multiforme, in both adult and pediatric patients) and non-glial tumors (such as medulloblastoma in pediatric patients). The history of a previous intracranial lesion is often the key to correct diagnosis, since, without prompting, neither the pathologist nor the radiologist is likely to think of a cervical node metastasis from a brain tumor when assessing a cervical mass of unknown etiology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.