ArticleBioinformatics (Oxford, England)2010
Association screening of common and rare genetic variants by penalized regression.
Article in Bioinformatics (Oxford, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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Who cites it
71 citing papers in PubMed.
- New statistical selection method for pleiotropic variants associated with both quantitative and qualitative traits.BMC bioinformatics · 2023Article
- Multivariate genome-wide association analysis by iterative hard thresholding.Bioinformatics (Oxford, England) · 2023Article
- A pyroptosis-related gene signature that predicts immune infiltration and prognosis in colon cancer.Frontiers in oncology · 2023Article
- Article
- A functional methylation signature to predict the prognosis of Chinese lung adenocarcinoma based on TCGA.Cancer medicine · 2022Article
- VCSEL: PRIORITIZING SNP-SET BY PENALIZED VARIANCE COMPONENT SELECTION.The annals of applied statistics · 2021Article
- DeepCOMBI: explainable artificial intelligence for the analysis and discovery in genome-wide association studies.NAR genomics and bioinformatics · 2021Article
- Article
- Iterative hard thresholding in genome-wide association studies: Generalized linear models, prior weights, and double sparsity.GigaScience · 2020Article
- OPENMENDEL: a cooperative programming project for statistical genetics.Human genetics · 2020Review
- Incorporating genetic networks into case-control association studies with high-dimensional DNA methylation data.BMC bioinformatics · 2019Article
- MULTILAYER KNOCKOFF FILTER: CONTROLLED VARIABLE SELECTION AT MULTIPLE RESOLUTIONS.The annals of applied statistics · 2019Article
- Fine mapping and subphenotyping implicates ADRA1B gene variants in psoriasis susceptibility in a Chinese population.Epigenomics · 2019Article
- Genomic prediction of relapse in recipients of allogeneic haematopoietic stem cell transplantation.Leukemia · 2019Article
- Iterative hard thresholding for model selection in genome-wide association studies.Genetic epidemiology · 2017Article
- The impact of rare and low-frequency genetic variants in common disease.Genome biology · 2017Review
- Longitudinal data analysis for rare variants detection with penalized quadratic inference function.Scientific reports · 2017Article
- Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data.Genetic epidemiology · 2017Article
- Controlling the Rate of GWAS False Discoveries.Genetics · 2017Article
- Prioritizing individual genetic variants after kernel machine testing using variable selection.Genetic epidemiology · 2016Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
motivationThis article extends our recent research on penalized estimation methods in genome-wide association studies to the realm of rare variants.
resultsThe new strategy is tested on both simulated and real data. Our findings on breast cancer data replicate previous results and shed light on variant effects within genes. AVAILABILITY: Rare variant discovery by group penalized regression is now implemented in the free program Mendel at http://www.genetics.ucla.edu/software/.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.