Evidence map›Paper›PMID 20691875›Full record

ArticleMethods in enzymology2010

Imaging mouse embryonic development.

Ryan S Udan, Mary E Dickinson

Abstract read
In one paragraph

Article in Methods in enzymology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Isoleucyl-tRNA synthetase 1 is essential for embryogenesis in mice.The Journal of veterinary medical science · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Live imaging mouse embryonic development: seeing is believing and revealing.Methods in molecular biology (Clifton, N.J.) · 2014
    Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ryan S UdanDepartment of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, Texas, USA.
Mary E Dickinson

Funding

Research Education and Career Horizons ProgramK12GM084897 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI SIFERS, RICHARD NORMAN, SLAUGHTER, GAYLE · 2008 to 2016
$8.3M
Neuro-Vascular RegenerationP20EB007076 · NIBIB · BAYLOR COLLEGE OF MEDICINE · PI HIRSCHI, KAREN KEMPER · 2006 to 2009
$4.4M
Imaging fluid forces in mouse cardiovascular developmentR01HL077187 · NHLBI · BAYLOR COLLEGE OF MEDICINE · PI DICKINSON, MARY E · 2005 to 2007
$1.1M
NHLBI NIH HHS R01 HL077187NIBIB NIH HHS P20 EB007076NIGMS NIH HHS K12 GM084897
6 · The paper itself

Abstract

For the past three decades, methods for culturing mouse embryos ex vivo have been optimized in order to improve embryo viability and physiology throughout critical stages of embryogenesis. Combining advances made in the production of transgenic animals and in the development of different varieties of fluorescent proteins (FPs), time-lapse imaging is becoming more and more popular in the analysis of dynamic events during mouse development. Targeting FPs to specific cell types or subcellular compartments has enabled researchers to study cell proliferation, apoptosis, migration, and changes in cell morphology in living mouse embryos in real time. Here we provide a guide for time-lapse imaging of early stages of mouse embryo development.

Indexed as

Embryonic DevelopmentMicroscopy, ConfocalAnimalsEmbryo Culture TechniquesEmbryo, MammalianFemaleFluorescent DyesMaleMicePregnancyRatsRats, Sprague-DawleyStaining and LabelingTime FactorsFluorescent Dyes

Identifiers

PMID20691875
PMCPMC5221674

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.