Evidence map›Paper›PMID 20691073›Full record

ArticleGenome medicine2010

Translational bioinformatics in the cloud: an affordable alternative.

Joel T Dudley, Yannick Pouliot, Rong Chen, Alexander A Morgan, Atul J Butte

Abstract read
In one paragraph

Article in Genome medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Parallel classification and feature selection in microarray data using SPRINT.Concurrency and computation : practice & experience · 2014
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Scientific research in the age of omics: the good, the bad, and the sloppy.Journal of the American Medical Informatics Association : JAMIA · 2013
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Opportunities and challenges for the life sciences community.Omics : a journal of integrative biology · 2012
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joel T DudleyProgram in Biomedical Informatics, Stanford University School of Medicine, 251 Campus Drive, Stanford, CA 94305, USA. jdudley@stanford.edu.
Yannick Pouliot
Rong Chen
Alexander A Morgan
Atul J Butte

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
Integrating Microarray and Proteomic Data by Ontology-based AnnotationR01LM009719 · NLM · STANFORD UNIVERSITY · PI BUTTE, ATUL J · 2008 to 2011
$1.1M
NLM NIH HHS R01 LM009719NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

With the continued exponential expansion of publicly available genomic data and access to low-cost, high-throughput molecular technologies for profiling patient populations, computational technologies and informatics are becoming vital considerations in genomic medicine. Although cloud computing technology is being heralded as a key enabling technology for the future of genomic research, available case studies are limited to applications in the domain of high-throughput sequence data analysis. The goal of this study was to evaluate the computational and economic characteristics of cloud computing in performing a large-scale data integration and analysis representative of research problems in genomic medicine. We find that the cloud-based analysis compares favorably in both performance and cost in comparison to a local computational cluster, suggesting that cloud computing technologies might be a viable resource for facilitating large-scale translational research in genomic medicine.

Identifiers

PMID20691073
PMCPMC2945008

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.