ReviewAnnual review of genomics and human genetics2010
Contrasting methods of quantifying fine structure of human recombination.
Review in Annual review of genomics and human genetics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 39 citations in OpenAlex.
- Inferring fine-scale rates of mutation and recombination in the coppery titi monkey (Plecturocebus cupreus).Heredity · 2026Article
- Recent Insights Into the Evolutionary Genomics of the Critically Endangered Aye-Aye (Daubentonia madagascariensis).American journal of primatology · 2025Review
- Inferring Fine-Scale Mutation and Recombination Rate Maps in Aye-Ayes (Ecology and evolution · 2025Article
- Novel Insights into the Landscape of Crossover and Noncrossover Events in Rhesus Macaques (Macaca mulatta).Genome biology and evolution · 2024Article
- Evaluation of the Genetic Diversity and Population Structure of Four Native Pig Populations in Gansu Province.International journal of molecular sciences · 2023Article
- From molecules to populations: appreciating and estimating recombination rate variation.Nature reviews. Genetics · 2020Review
- Interrogating the Functions of PRDM9 Domains in Meiosis.Genetics · 2018Article
- Construction of PRDM9 allele-specific recombination maps in cattle using large-scale pedigree analysis and genome-wide single sperm genomics.DNA research : an international journal for rapid publication of reports on genes and genomes · 2018Article
- Effects of Demographic History on the Detection of Recombination Hotspots from Linkage Disequilibrium.Molecular biology and evolution · 2018Article
- Background selection as null hypothesis in population genomics: insights and challenges fromPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Recombination correlates with synaptonemal complex length and chromatin loop size in bovids-insights into mammalian meiotic chromosomal organization.Chromosoma · 2017Article
- The Time Scale of Recombination Rate Evolution in Great Apes.Molecular biology and evolution · 2016Article
- Strong artificial selection in domestic mammals did not result in an increased recombination rate.Molecular biology and evolution · 2015Article
- The 8p23 inversion polymorphism determines local recombination heterogeneity across human populations.Genome biology and evolution · 2014Article
- Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences.BMC bioinformatics · 2014Article
- Recombination rates and genomic shuffling in human and chimpanzee--a new twist in the chromosomal speciation theory.Molecular biology and evolution · 2013Article
- Inferring genome-wide recombination landscapes from advanced intercross lines: application to yeast crosses.PloS one · 2013Article
- Recombination is associated with the evolution of genome structure and worker behavior in honey bees.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Article
- Recombination rate variation in closely related species.Heredity · 2011Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
There has been considerable excitement over the ability to construct linkage maps based only on genome-wide genotype data for single nucleotide polymorphic sites (SNPs) in a population sample. These maps, which are derived from estimates of linkage disequilibrium (LD), rely on population genetics theory to relate the decay of LD to the local rate of recombination, but other population processes also come into play. Here we contrast these LD maps to the classically derived, pedigree-based human recombination maps. The LD maps have a level of resolution greatly exceeding that of the pedigree maps, and at this fine scale, sperm typing allows a means of validation. While at a gross level both the pedigree maps and the sperm typing methods generally agree with LD maps, there are significant local differences between them, and the fact that these maps measure different genetic features should be remembered when using them for other genetic inferences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.