Trial reportIntensive care medicine2010
Patients' prediction of extubation success.
Trial report in Intensive care medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled Analysis of Central Venous Pressure and Brain Natriuretic Peptide Levels in Patients With Extubation Failure.Frontiers in physiology · 2022Pooled it
- Intermittent noninvasive ventilation after extubation in patients with chronic respiratory disorders: a multicenter randomized controlled trial (VHYPER).Intensive care medicine · 2017Trial
- Clinical Predictors of Weaning Failure and Mortality in Individuals With COVID-19 Undergoing Invasive Mechanical Ventilation: A Retrospective Cohort Study.Pulmonary medicine · 2026Article
- Bridging the Gap: The Role of Non-Invasive Respiratory Supports in Weaning from Invasive Mechanical Ventilation.Journal of clinical medicine · 2025Review
- Prolonged weaning from mechanical ventilation: who, what, when and how?Breathe (Sheffield, England) · 2024Review
- Predictive Value of Serial Rapid Shallow Breathing Index Measurements for Extubation Success in Intensive Care Unit Patients.Medicina (Kaunas, Lithuania) · 2024Observational
- Work of Breathing During Proportional Assist Ventilation as a Predictor of Extubation Failure.Respiratory care · 2023Observational
- Respiratory distress observation scales to predict weaning outcome.Critical care (London, England) · 2022Article
- Development and Validation of a Machine-Learning Model for Prediction of Extubation Failure in Intensive Care Units.Frontiers in medicine · 2021Article
- A Simple Weaning Model Based on Interpretable Machine Learning Algorithm for Patients With Sepsis: A Research of MIMIC-IV and eICU Databases.Frontiers in medicine · 2021Article
- Predicting weaning difficulty for planned extubation patients with an artificial neural network.Medicine · 2019Article
- The importance of timing for the spontaneous breathing trial.Annals of translational medicine · 2019Article
- Extubation success can be better predicted by diaphragmatic excursion using ultrasound compared to rapid shallow breathing index.Indian journal of anaesthesia · 2018Article
- An Artificial Neural Network Model for Predicting Successful Extubation in Intensive Care Units.Journal of clinical medicine · 2018Article
- Ten reasons to be more attentive to patients when setting the ventilator.Intensive care medicine · 2016Article
- Extubation outcome after a successful spontaneous breathing trial: A multicenter validation of a 3-factor prediction model.Experimental and therapeutic medicine · 2015Article
- Managing the apparent and hidden difficulties of weaning from mechanical ventilation.Intensive care medicine · 2013Review
- The association between comorbid illness, colonization status, and acute hospitalization in patients receiving prolonged mechanical ventilation.Respiratory care · 2013Article
- Year in review in Intensive Care Medicine 2010: III. ARDS and ALI, mechanical ventilation, noninvasive ventilation, weaning, endotracheal intubation, lung ultrasound and paediatrics.Intensive care medicine · 2011Article
- What's New in Critical Illness and Injury Science? Extubation Failure Predictors for 2016.International journal of critical illness and injury scienceArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe spontaneous breathing trial (SBT)-relying on objective criteria assessed by the clinician-is the major diagnostic tool to determine if patients can be successfully extubated. However, little is known regarding the patient's subjective perception of autonomous breathing.
methodsWe performed a prospective observational study in 211 mechanically ventilated adult patients successfully completing a SBT. Patients were randomly assigned to be interviewed during this trial regarding their prediction of extubation success. We compared post-extubation outcomes in three patient groups: patients confident (confidents; n = 115) or not (non-confidents; n = 38) of their extubation success and patients not subjected to interview (control group; n = 58).
resultsExtubation success was more frequent in confidents than in non-confidents (90 vs. 45%; p < 0.001/positive likelihood ratio = 2.00) or in the control group (90 vs. 78%; p = 0.04). On the contrary, extubation failure was more common in non-confidents than in confidents (55 vs. 10%; p < 0.001/negative likelihood ratio = 0.19). Logistic regression analysis showed that extubation success was associated with patient's prediction [OR (95% CI): 9.2 (3.74-22.42) for confidents vs.non-confidents] as well as to age [0.72 (0.66-0.78) for age 75 vs. 65 and 1.31 (1.28-1.51) for age 55 vs. 65].
conclusionsOur data suggest that at the end of a sustained SBT, extubation success might be correlated to the patients' subjective perception of autonomous breathing. The results of this study should be confirmed by a large multicenter trial.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.