Evidence map›Paper›PMID 20689674›Full record

ArticlePET clinics2010

FDG PET in the Evaluation of Parkinson's Disease.

Kathleen L Poston, David Eidelberg

Open access · greenAbstract read
In one paragraph

Article in PET clinics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Motor signs in late life depression relate to altered subcortical synaptic density and gray matter volume: anNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  4. Article
  5. Cognitive disorders and parkinson's disease: a literature review.Journal of neural transmission (Vienna, Austria : 1996) · 2025
    Review
  6. Dopamine-responsive post-anoxic parkinsonism.Journal of Parkinson's disease · 2025
    Article
  7. Parkinson's disease cerebrovascular reactivity pattern: A feasibility study.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Article
  14. Recent Advances in Biomarkers for Parkinson's Disease.Frontiers in aging neuroscience · 2018
    Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kathleen L Poston
David Eidelberg
Feinstein Institute for Medical Research · USStanford Medicine · US

Funding

TRANSLATIONAL APPROACHES TO NEUROPROTECTION OF AXONS IN PDrP50NS038370 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BURKE, ROBERT E · 1999 to 2014
$24.0M
WHITE MATTER STRUCTURAL DEFICITS IN HIGH FUNCTIONING CHILDREN WITH AUTISM SPEM01RR018535 · NCRR · FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH · PI SCHWARTZ, GUY · 2003 to 2010
$19.5M
PET IN PARKINSONISM: A MULTICENTER COLLABORATIVE STUDYR01NS035069 · NINDS · NORTH SHORE UNIVERSITY HOSPITAL · PI EIDELBERG, DAVID · 1996 to 2003
$3.4M
NCRR NIH HHS M01 RR018535NINDS NIH HHS P50 NS038370NINDS NIH HHS R01 NS035069
6 · The paper itself

Abstract

Network analysis of (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) is an innovative approach for the study of in movement disorders, such as Parkinson's disease (PD). Spatial covariance analysis of imaging data acquired from PD patients has revealed characteristic regional patterns associated with the motor and cognitive features of disease. Quantification of pattern expression in individual patients can be used for diagnosis, assessment of disease severity, and evaluation of novel medical and surgical therapies. Identification of disease-specific patterns in other parkinsonian syndromes, such as multiple system atrophy and progressive supranuclear palsy, has improved diagnostic accuracy in patients with difficult to diagnose parkinsonism. Further developments of these techniques are likely to enhance the role of functional imaging in investigating underlying abnormalities and potential new therapies in these neurodegenerative diseases.

Identifiers

PMID20689674
PMCPMC2913894
OpenAlexW1962229341

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.