Evidence map›Paper›PMID 20689423›Full record

ReviewCurrent opinion in infectious diseases2010

Shigellosis update: advancing antibiotic resistance, investment empowered vaccine development, and green bananas.

Margaret Kosek, Pablo Peñataro Yori, Maribel Paredes Olortegui

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 52 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Margaret KosekDepartment of International Health, Johns Hopkins School of Public Health, Baltimore, Maryland, USA. mkosek@jhsph.edu
Pablo Peñataro Yori
Maribel Paredes Olortegui
Johns Hopkins University · USPrisma · PE

Funding

Epidemiology of Shigellosis in the Peruvian AmazonK01TW005717 · FIC · JOHNS HOPKINS UNIVERSITY · PI KOSEK, MARGARET N · 2001 to 2007
$615k
FIC NIH HHS K01 TW005717FIC NIH HHS K01-TW571709
6 · The paper itself

Abstract

purpose of reviewShigella is the principal cause of clinical dysentery and an important cause of morbidity and mortality among children in impoverished regions. The purpose of this review is to present key findings in the areas of epidemiology, disease control, and treatment of shigellosis. RECENT

findingsRecent research activity has advanced the understanding of the epidemiology and host-pathogen interactions. Increased investment and activity in the area of vaccine development have lead to a diversification of candidates and ongoing technical advances yet continue to yield disappointing results in clinical trials in endemic populations and among the most relevant age groups (children under 2 years of age). The description of the rapid spread of quinolone resistance requires monitoring to ensure appropriate case management, particularly in south-east Asia. The evaluation of adjunctive nutritional therapy in endemic areas has supported the use of green bananas in shortening the duration of Shigella dysentery and persistent diarrhea due to Shigella, as well as improving weight gain in early convalescence. SUMMARY: Despite a great level of activity in basic sciences, there continues to be a large gap in the ability to translate these findings into disease control measures or therapeutic options for individuals living in areas in which shigellosis is endemic.

Indexed as

DietDrug Resistance, BacterialMusaAnti-Bacterial AgentsClinical Trials as TopicDysentery, BacillaryHumansShigellaShigella VaccinesAnti-Bacterial AgentsShigella Vaccines

Identifiers

PMID20689423
PMCPMC6892429
OpenAlexW2045435483

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.