Evidence map›Paper›PMID 20689191›Full record

ArticleIndian journal of ophthalmology

Comparison of serum glycosylated hemoglobin levels in patients with diabetic cystoid macular edema with and without serous macular detachment.

Burak Turgut, Fatih Cem Gul, Nevin Ilhan, Tamer Demir, Ulku Celiker

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Indian journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Burak TurgutDepartment of Ophthalmology, Firat University School of Medicine, Elazig, Turkey.
Fatih Cem Gul
Nevin Ilhan
Tamer Demir
Ulku Celiker
Fırat University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimA clinical comparative trial was conducted to compare the levels of glycosylated hemoglobin (HbA1c) in patients with diabetic cystoid macular edema (CME) with and without serous macula detachment (SMD). MATERIALS AND

methodsThirty patients (group 1) with diabetic CME in both eyes, but without SMD, and 30 patients (group 2) with diabetic CME and SMD in both eyes documented by optical coherence tomography (OCT) and fundus fluorescein angiography (FFA), were included in the study. In addition to the measurement of central macular thickness by OCT and visual acuity (VA) (as logMAR) using the the early treatment diabetic retinopathy study (ETDRS) chart, the concentrations of HbA1c were measured by high performance liquid chromatography (HPLC). Statistical analysis was done by independent samples t test.

resultsThe mean logMAR VA was 0.8 +/- 0.22 (1.0-0.5) in group 1 and 0.7 +/- 0.16 (1.0-0.6) in group 2. The mean central macular thickness, as determined by OCT, was 468.70 +/- 70.44 microm (344-602 microm) in group 1 and 477.80 +/- 73.34 microm (354-612 microm) in group 2. The difference between the groups was not statistically significant (P = 0.626). The mean HbA1c levels were 8.16 +/- 0.99% in group 1 and 10.05 +/- 1.66% in group 2. The difference between the groups was statistically significant (P < 0.001).

conclusionsThe presence of SMD and high HbA1c levels in the patients with diabetic CME may be indirectly suggestive of retinal pigment epithelium dysfunction.

Indexed as

Macula LuteaAgedDiabetic RetinopathyFemaleFluorescein AngiographyFundus OculiGlycated HemoglobinHumansMacular EdemaMaleMiddle AgedRetinal DetachmentTomography, Optical CoherenceVisual AcuityGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID20689191
PMCPMC2992911
OpenAlexW2030017309

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.