ArticleAmerican journal of epidemiology2010
The emergence of translational epidemiology: from scientific discovery to population health impact.
Article in American journal of epidemiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 6 of them syntheses that pooled it.
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Who cites it
104 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use.The Cochrane database of systematic reviews · 2024Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting diet, physical activity, obesity, tobacco or alcohol use.The Cochrane database of systematic reviews · 2022Pooled it
- Strategies for enhancing the implementation of school-based policies or practices targeting risk factors for chronic disease.The Cochrane database of systematic reviews · 2017Pooled it
- Precocious cervical ripening as a screening target to predict spontaneous preterm delivery among asymptomatic singleton pregnancies: a systematic review.American journal of obstetrics and gynecology · 2015Pooled it
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement.European journal of human genetics : EJHG · 2011Guideline
- Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement.PLoS medicine · 2011Guideline
- Efficacy of an HIV intervention in reducing high-risk human papillomavirus, nonviral sexually transmitted infections, and concurrency among African American women: a randomized-controlled trial.Journal of acquired immune deficiency syndromes (1999) · 2013Trial
- Evaluating the effectiveness and implementation of evidence-based treatment: A multisite hybrid design.The American psychologistTrial
- Translational stewardship in pandemic therapeutics: ivermectin, evidentiary misalignment, and the propagation of constraints.Journal of translational medicine · 2026Article
- From discovery to delivery: a systems-based pathway for translating science into global and humanitarian health impact.Conflict and health · 2026Article
- Combining Therapeutic Strategies to Treat the Injured Spinal Cord: A Translational Perspective.Journal of neurotrauma · 2025Review
- Concept analysis of health research translation nomenclature.BMJ open quality · 2025Article
- Identification of Clusters in a Population With Obesity Using Machine Learning: Secondary Analysis of The Maastricht Study.JMIR medical informatics · 2025Article
- Review
- Development and application of the RaphaAmerican journal of translational research · 2024Article
- The challenges of epidemiologic translation: communicating with physicians, policymakers, and the public.Frontiers in public health · 2024Article
- Scope highlights ofAnnals of translational medicine · 2023Article
- Closing the gap: sex-related differences in osteoarthritis and the ongoing need for translational studies.Annals of translational medicine · 2023Article
- Comparative Analysis of Clinical Practice Guidelines for the Pharmacological Treatment of Type 2 Diabetes Mellitus in Latin America.Current diabetes reports · 2023Review
- The potential link between dietary factors and patient recovery in orthopedic surgery research.Frontiers in nutrition · 2023Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent emphasis on translational research (TR) is highlighting the role of epidemiology in translating scientific discoveries into population health impact. The authors present applications of epidemiology in TR through 4 phases designated T1-T4, illustrated by examples from human genomics. In T1, epidemiology explores the role of a basic scientific discovery (e.g., a disease risk factor or biomarker) in developing a "candidate application" for use in practice (e.g., a test used to guide interventions). In T2, epidemiology can help to evaluate the efficacy of a candidate application by using observational studies and randomized controlled trials. In T3, epidemiology can help to assess facilitators and barriers for uptake and implementation of candidate applications in practice. In T4, epidemiology can help to assess the impact of using candidate applications on population health outcomes. Epidemiology also has a leading role in knowledge synthesis, especially using quantitative methods (e.g., meta-analysis). To explore the emergence of TR in epidemiology, the authors compared articles published in selected issues of the Journal in 1999 and 2009. The proportion of articles identified as translational doubled from 16% (11/69) in 1999 to 33% (22/66) in 2009 (P = 0.02). Epidemiology is increasingly recognized as an important component of TR. By quantifying and integrating knowledge across disciplines, epidemiology provides crucial methods and tools for TR.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.