ArticleGenome biology and evolution2010
Evolutionary dynamics of complete Campylobacter pan-genomes and the bacterial species concept.
Article in Genome biology and evolution, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
65 citing papers in PubMed, 108 citations in OpenAlex.
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- A social niche breadth score reveals niche range strategies of generalists and specialists.Nature ecology & evolution · 2023Article
- Genome-Wide Pathway Exploration of theMicroorganisms · 2023Article
- Gene flow and introgression are pervasive forces shaping the evolution of bacterial species.Genome biology · 2022Article
- Pan-Genome Analysis of Campylobacter: Insights on the Genomic Diversity and Virulence Profile.Microbiology spectrum · 2022Article
- Differences in the Propensity of Different Antimicrobial Resistance Determinants to Be Disseminated via Transformation inMicroorganisms · 2022Article
- Comparative Genome Analysis ofFrontiers in genetics · 2021Article
- The Origin of Niches and Species in the Bacterial World.Frontiers in microbiology · 2021Review
- A 19-isolate reference-quality global pangenome for the fungal wheat pathogen Zymoseptoria tritici.BMC biology · 2020Article
- Horizontal genetic exchange of chromosomally encoded markers between Campylobacter jejuni cells.PloS one · 2020Article
- Characterization ofFrontiers in genetics · 2020Article
- Distinctive features gleaned from the comparative genomes analysis of clinical and non-clinical isolates of Klebsiella pneumoniae.Bioinformation · 2020Article
- Viability Quantitative PCR Utilizing Propidium Monoazide, Spheroplast Formation, and Campylobacter coli as a Bacterial Model.Applied and environmental microbiology · 2019Article
- Article
- Pan-genome analyses of model fungal species.Microbial genomics · 2019Article
- Article
- Clustering of Pan- and Core-genome of Lactobacillus provides Novel Evolutionary Insights for Differentiation.BMC genomics · 2018Article
- Diversification of Secondary Metabolite Biosynthetic Gene Clusters Coincides with Lineage Divergence in Streptomyces.Antibiotics (Basel, Switzerland) · 2018Article
- Genetic Competence Drives Genome Diversity in Bacillus subtilis.Genome biology and evolution · 2018Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Defining bacterial species and understanding the relative cohesiveness of different components of their genomes remains a fundamental problem in microbiology. Bacterial species tend to be comprised of both a set of core and dispensable genes, with the sum of these two components forming the species pan-genome. The role of the core and dispensable genes in defining bacterial species and the question of whether pan-genomes are finite or infinite remain unclear. Here we demonstrate, through the analysis of 96 genome sequences derived from two closely related sympatric sister species of pathogenic bacteria (Campylobacter coli and C. jejuni), that their pan-genome is indeed finite and that there are unique and cohesive features to each of their genomes defining their genomic identity. The two species have a similar pan-genome size; however, C. coli has acquired a larger core genome and each species has evolved a number of species-specific core genes, possibly reflecting different adaptive strategies. Genome-wide assessment of the level of lateral gene transfer within and between the two sister species, as well as within the core and non-core genes, demonstrates a resistance to interspecies recombination in the core genome of the two species and therefore provides persuasive support for the core genome hypothesis for bacterial species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.