Evidence map›Paper›PMID 20687745›Full record

ArticleThe Review of scientific instruments2010

Magnet polepiece design for uniform magnetic force on superparamagnetic beads.

Todd Fallesen, David B Hill, Matthew Steen, Jed C Macosko, Keith Bonin, George Holzwarth

Open access · bronzeAbstract read
In one paragraph

Article in The Review of scientific instruments, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Todd FallesenDepartment of Physics, Wake Forest University, Winston-Salem, North Carolina 27109, USA.
David B Hill
Matthew Steen
Jed C Macosko
Keith Bonin
George Holzwarth
Wake Forest University · USUniversity of North Carolina at Chapel Hill · US

Funding

Kinesin Velocity-Force Curves when 1,2, or 3 motors transport a single loadR15NS053493 · NINDS · WAKE FOREST UNIVERSITY · PI HOLZWARTH, GEORGE M · 2006 to 2006
$128k
NINDS NIH HHS NS053493NINDS NIH HHS R15 NS053493
6 · The paper itself

Abstract

Here we report construction of a simple electromagnet with novel polepieces which apply a spatially uniform force to superparamagnetic beads in an optical microscope. The wedge-shaped gap was designed to keep partial differential B(x)/ partial differential y constant and B large enough to saturate the bead. We achieved fields of 300-600 mT and constant gradients of 67 T/m over a sample space of 0.5x4 mm(2) in the focal plane of the microscope and 0.05 mm along the microscope optic axis. Within this space the maximum force on a 2.8 microm diameter Dynabead was 12 pN with a spatial variation of approximately 10%. Use of the magnet in a biophysical experiment is illustrated by showing that gliding microtubules propelled by the molecular motor kinesin can be stopped by the force of an attached magnetic bead.

Indexed as

MagneticsMicrospheresImaging, Three-DimensionalMicroscopyMotion

Identifiers

PMID20687745
PMCPMC2924904
OpenAlexW1972564040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.