ReviewPflugers Archiv : European journal of physiology2010
A comprehensive analysis of gene expression profiles in distal parts of the mouse renal tubule.
Review in Pflugers Archiv : European journal of physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 34 citations in OpenAlex.
- Perturbation of the circadian clock in chronic diseases involving organ fibrosis.The Journal of clinical investigation · 2025Review
- Urine albumin-to-creatinine ratio diurnal variation rate predicts outcomes in idiopathic membranous nephropathy.Clinical and experimental nephrology · 2024Article
- Adhesion G protein-coupled receptor gluing action guides tissue development and disease.Journal of molecular medicine (Berlin, Germany) · 2022Review
- Multiomic analysis of the Arabian camel (Camelus dromedarius) kidney reveals a role for cholesterol in water conservation.Communications biology · 2021Article
- The serine-threonine kinase PIM3 is an aldosterone-regulated protein in the distal nephron.Physiological reports · 2019Article
- Recapitulating kidney development: Progress and challenges.Seminars in cell & developmental biology · 2019Review
- Circadian Clock Genes in Diabetic Kidney Disease (DKD).Current diabetes reports · 2019Review
- Article
- Circadian rhythms and the kidney.Nature reviews. Nephrology · 2018Review
- RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action.Physiological genomics · 2018Article
- Adhesion GPCRs in Kidney Development and Disease.Frontiers in cell and developmental biology · 2018Review
- Comparative transcriptomic analysis identifies evolutionarily conserved gene products in the vertebrate renal distal convoluted tubule.Pflugers Archiv : European journal of physiology · 2017Article
- New insights into sodium transport regulation in the distal nephron: Role of G-protein coupled receptors.World journal of biological chemistry · 2016Review
- RNA sequencing of the nephron transcriptome: a technical note.Kidney research and clinical practice · 2015Article
- A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells.Scientific reports · 2015Article
- Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30.American journal of physiology. Renal physiology · 2014Article
- The multiple signaling modalities of adhesion G protein-coupled receptor GPR126 in development.Receptors & clinical investigation · 2014Article
- Characterization of the kidney transcriptome of the South American olive mouse Abrothrix olivacea.BMC genomics · 2014Article
- Protein phosphatase 1 inhibitor-1 deficiency reduces phosphorylation of renal NaCl cotransporter and causes arterial hypotension.Journal of the American Society of Nephrology : JASN · 2014Article
- Semicircular canal morphogenesis in the zebrafish inner ear requires the function of gpr126 (lauscher), an adhesion class G protein-coupled receptor gene.Development (Cambridge, England) · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The distal parts of the renal tubule play a critical role in maintaining homeostasis of extracellular fluids. In this review, we present an in-depth analysis of microarray-based gene expression profiles available for microdissected mouse distal nephron segments, i.e., the distal convoluted tubule (DCT) and the connecting tubule (CNT), and for the cortical portion of the collecting duct (CCD; Zuber et al., Proc Natl Acad Sci USA 106:16523-16528, 2009). Classification of expressed transcripts in 14 major functional gene categories demonstrated that all principal proteins involved in maintaining the salt and water balance are represented by highly abundant transcripts. However, a significant number of transcripts belonging, for instance, to categories of G-protein-coupled receptors or serine/threonine kinases exhibit high expression levels but remain unassigned to a specific renal function. We also established a list of genes differentially expressed between the DCT/CNT and the CCD. This list is enriched by genes related to segment-specific transport functions and by transcription factors directing the development of the distal nephron or collecting ducts. Collectively, this in silico analysis provides comprehensive information about relative abundance and tissue specificity of the DCT/CNT and the CCD expressed transcripts and identifies new candidate genes for renal homeostasis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.