Trial reportSkeletal radiology2011
Combination radiofrequency ablation and cementoplasty for palliative treatment of painful neoplastic bone metastasis: experience with 53 treated lesions in 36 patients.
Trial report in Skeletal radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 141 citations in OpenAlex.
- Radiofrequency Ablation of Painful Spinal Metastasis: A Systematic Review.Current oncology (Toronto, Ont.) · 2025Pooled it
- Thermal ablation to relieve pain from metastatic bone disease: a systematic review.Skeletal radiology · 2019Pooled it
- Vertebral Augmentation Involving Vertebroplasty or Kyphoplasty for Cancer-Related Vertebral Compression Fractures: A Systematic Review.Ontario health technology assessment series · 2016Pooled it
- Interventional Radiology in the Treatment of Musculoskeletal Tumours.Current oncology (Toronto, Ont.) · 2026Review
- Evaluation of the therapeutic efficacy of precise microwave ablation combined with spinal tumor separation surgery for managing spinal metastases.BMC musculoskeletal disorders · 2026Article
- Locoregional Non-Surgical Treatments for Unresectable or Oligometastatic Sarcomas: A Literature Review.Current treatment options in oncology · 2025Review
- Minimally invasive interventional guided imaging therapies of musculoskeletal tumors.Quantitative imaging in medicine and surgery · 2024Review
- Effectiveness of RF ablation and cementoplasty in enhancing functional capacity in pelvic malignant bone metastases.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- Cementoplasty to cryoablation: review and current status.BJR open · 2024Review
- Radiofrequency Ablation in Vertebral Body Metastasis with and without Percutaneous Cement Augmentation: A Systematic Review Addressing the Need for SPINE Stability Evaluation.Diagnostics (Basel, Switzerland) · 2023Review
- Image-Guided Percutaneous Ablation for Primary and Metastatic Tumors.Diagnostics (Basel, Switzerland) · 2022Review
- CIRSE Standards of Practice on Thermal Ablation of Bone Tumours.Cardiovascular and interventional radiology · 2022Article
- A Retrospective Evaluation of Operative and Postoperative Outcomes in Patients with Spinal Metastases from a Single Center to Compare Vertebrectomy with Combined Vertebrectomy and Radiofrequency Ablation.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Comparison of the postoperative pain change and spinal stenosis rate between percutaneous vertebroplasty combined with radiofrequency ablation and withJournal of interventional medicine · 2021Article
- Role of radiofrequency ablation and cement injection for pain control in patients with spinal metastasis.BMC musculoskeletal disorders · 2021Article
- Radiofrequency ablation and balloon kyphoplasty for palliation of painful spinal metastases.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
- Computer-Assisted Surgical Navigation for Primary and Metastatic Bone Malignancy of the Pelvis: Current Evidence and Future Directions.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2021Review
- Current Overview of Treatment for Metastatic Bone Disease.Current oncology (Toronto, Ont.) · 2021Review
- Temperature Monitoring in Hyperthermia Treatments of Bone Tumors: State-of-the-Art and Future Challenges.Sensors (Basel, Switzerland) · 2021Review
- Management of Spinal Bone Metastases With Radiofrequency Ablation, Vertebral Reinforcement and Transpedicular Fixation: A Retrospective Single-Center Case Series.Frontiers in oncology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe report the safety and efficacy of combined radiofrequency ablation and cementoplasty in treating painful neoplastic bone lesions. MATERIALS AND
methodsFifty-three combined radiofrequency ablation and cementoplasty procedures were completed in 36 patients. Thirty-four vertebrae (20 lumbar, 14 thoracic), 14 acetabulae, 3 sacra, 1 pubic symphysis, and 1 humerus were treated. Patient age ranged from 34 to 81 years (mean 57.6 years, SD=12.6). Primary malignancies included: 12 breast, 5 lung, 6 multiple myeloma, 2 prostate, 2 renal cell carcinoma, 1 synovial sarcoma, 1 endometrial, 1 oral squamous cell carcinoma, 1 lymphoma, 1 colon, 1 transitional cell carcinoma, 1 colorectal, 1 cholangiocarcinoma, and 1 pheochromocytoma. Primary neoplasm location, pain levels pre- and post-procedure (as assessed using the Visual Analog Scale), number of radiofrequency (RF) treatments and any extravasation were documented.
resultsCombined radiofrequency ablation (RFA) and cementoplasty procedures were performed with 100% technical success (53 out of 53). The mean pre-procedure and post-procedure pain, as measured by the Visual Analog Scale (VAS), was 7.2/10 and 3.4/10 respectively. Symptomatic complications included one case of self-resolving transient thermal sciatic neurapraxia following RFA and acetabuloplasty. Two cases of transient pain following epidural leaks during treatment of thoracic vertebrae and breast metastases also occurred. Non-symptomatic complications, from a variety of cases, included cement emboli to the lung, incidental, non-symptomatic leaks into the needle track, spinal canal, draining veins, disc spaces, and an intra-articular leak into the hip joint.
conclusionCombined RFA and cementoplasty appears to be safe, practical and effective in the palliative treatment of painful neoplastic lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.