Evidence map›Paper›PMID 20686444›Full record

ReviewTransplantation2010

The significance of non-T-cell pathways in graft rejection: implications for transplant tolerance.

Xian Chang Li

Abstract readEditorialReview
In one paragraph

Review in Transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Mast cells participate in allograft rejection: can IL-37 play an inhibitory role?Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Review
  5. Macrophage subpopulations and their impact on chronic allograft rejection versus graft acceptance in a mouse heart transplant model.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2018
    Article
  6. The future of cardiac transplantation.Annals of cardiothoracic surgery · 2018
    Article
  7. Review
  8. Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2016
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Regulatory immune cells in transplantation.Nature reviews. Immunology · 2012
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Xian Chang Li

Funding

Mechanisms mediating CD28 &CD154 independent rejectionR01AI057409 · NIAID · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LI, XIAN CHANG · 2004 to 2010
$1.8M
Mechanisms of OX40 in peripheral transplant toleranceR01AI070315 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI LI, XIAN CHANG · 2007 to 2011
$1.7M
NIAID NIH HHS R01 AI057409NIAID NIH HHS R01 AI070315
6 · The paper itself

Abstract

Both innate and adaptive immune cells are actively involved in the initiation and destruction of allotransplants, and there is a true need now to look beyond T cells in the allograft response, examining various non-T-cell types in transplant models and how such cell types interact with T cells in determining the fate of an allograft. Studies in this area may lead to further improvement in transplant outcomes.

Indexed as

AnimalsB-LymphocytesDendritic CellsGraft RejectionGraft SurvivalHumansKiller Cells, NaturalMacrophagesMast CellsMiceModels, ImmunologicalMonocytesT-LymphocytesTransplantation Tolerance

Identifiers

PMID20686444
PMCPMC3015014

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.