Evidence map›Paper›PMID 20686080›Full record

ArticleJournal of clinical microbiology2010

Relatedness of human and animal Clostridium difficile PCR ribotype 078 isolates determined on the basis of multilocus variable-number tandem-repeat analysis and tetracycline resistance.

D Bakker, J Corver, C Harmanus, A Goorhuis, E C Keessen, W N Fawley, M H Wilcox, E J Kuijper

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 110 citations in OpenAlex.

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  4. Systems biology approach to functionally assess theProceedings of the National Academy of Sciences of the United States of America · 2022
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  6. Genetic Relatedness of 5-Year Isolates ofAntibiotics (Basel, Switzerland) · 2021
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  7. Article
  8. Pet Ownership Protects Against Recurrence ofOpen forum infectious diseases · 2020
    Article
  9. Article
  10. Article
  11. Emerging microbes & infections · 2019
    Review
  12. Genomic Delineation of Zoonotic Origins ofFrontiers in public health · 2019
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The emergence of Clostridium difficile PCR-ribotype 001 in Slovakia.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

D BakkerDepartment of Medical Microbiology, Center of Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
J Corver
C Harmanus
A Goorhuis
E C Keessen
W N Fawley
M H Wilcox
E J Kuijper
Leiden University Medical Center · NLLeeds Teaching Hospitals NHS Trust · GBUniversity of Leeds · GBUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Totals of 102 and 56 Clostridium difficile type 078 strains of human and porcine origins, respectively, from four European countries were investigated by an optimized multilocus variable-number tandem-repeat analysis (MLVA) and for tetracycline susceptibility. Eighty-five percent of all isolates were genetically related, irrespective of human or porcine origin. Human strains were significantly more resistant to tetracycline than porcine strains. All tetracycline-resistant strains contained the Tn916-like transposon harboring the tet(M) gene. We conclude that strains from human and porcine origins are genetically related, irrespective of the country of origin. This may reflect a lack of diversity and/or common source.

Indexed as

DNA FingerprintingTetracycline ResistanceAnimalsBacterial Typing TechniquesClostridioides difficileClostridium InfectionsCluster AnalysisDNA, BacterialDNA Transposable ElementsEuropeGenotypeHumansMinisatellite RepeatsPolymerase Chain ReactionRibotypingSwineDNA, BacterialDNA Transposable Elements

Identifiers

PMID20686080
PMCPMC2953124
OpenAlexW2130678483

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.