ArticleJournal of virology2010
Crystallographic structure of porcine adenovirus type 4 fiber head and galectin domains.
Article in Journal of virology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- From examining the relationship between (corona)viral adhesins and galectins to glyco-perspectives.Biophysical journal · 2021Article
- Virus recognition of glycan receptors.Current opinion in virology · 2019Review
- Structure and N-acetylglucosamine binding of the distal domain of mouse adenovirus 2 fibre.The Journal of general virology · 2018Article
- Crystal structure of raptor adenovirus 1 fibre head and role of the beta-hairpin in siadenovirus fibre head domains.Virology journal · 2016Article
- Crystal structure of the fibre head domain of bovine adenovirus 4, a ruminant atadenovirus.Virology journal · 2015Article
- Structure and Sialyllactose Binding of the Carboxy-Terminal Head Domain of the Fibre from a Siadenovirus, Turkey Adenovirus 3.PloS one · 2015Article
- Article
- Structural analysis of the evolutionary origins of influenza virus hemagglutinin and other viral lectins.Journal of virology · 2013Article
- An adenovirus vector incorporating carbohydrate binding domains utilizes glycans for gene transfer.PloS one · 2013Article
- Latest insights on adenovirus structure and assembly.Viruses · 2012Review
- Structural basis for norovirus inhibition and fucose mimicry by citrate.Journal of virology · 2012Article
- Chapter two--Adenovirus strategies for tissue-specific targeting.Advances in cancer research · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Adenovirus isolate NADC-1, a strain of porcine adenovirus type 4, has a fiber containing an N-terminal virus attachment region, shaft and head domains, and a C-terminal galectin domain connected to the head by an RGD-containing sequence. The crystal structure of the head domain is similar to previously solved adenovirus fiber head domains, but specific residues for binding the coxsackievirus and adenovirus receptor (CAR), CD46, or sialic acid are not conserved. The structure of the galectin domain reveals an interaction interface between its two carbohydrate recognition domains, locating both sugar binding sites face to face. Sequence evidence suggests other tandem-repeat galectins have the same arrangement. We show that the galectin domain binds carbohydrates containing lactose and N-acetyl-lactosamine units, and we present structures of the galectin domain with lactose, N-acetyl-lactosamine, 3-aminopropyl-lacto-N-neotetraose, and 2-aminoethyl-tri(N-acetyl-lactosamine), confirming the domain as a bona fide galectin domain.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.