ArticleBiology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation2010
Factors associated with self-reported physical and mental health after hematopoietic cell transplantation.
Article in Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Literature Review and Head-to-Head Comparison of Social Support and Social Constraint in Relation to the Psychological Functioning of Cancer Survivors.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2020Pooled it
- The influence of social support on hematopoietic stem cell transplantation survival: a systematic review of literature.PloS one · 2013Pooled it
- Developing a Risk Prediction Model for Long-Term Physical and Psychological Functioning after Hematopoietic Cell Transplantation.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016Trial
- Social support, social constraint, and psychological adjustment in patients with colorectal cancer.Journal of behavioral medicine · 2025Article
- Oral Health-Related Quality of Life After Allogeneic Bone Marrow Transplant-A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Association between positive affect, flourishing, quality of life, and psychological distress in allogeneic hematopoietic stem cell transplantation.Journal of psychosocial oncology · 2025Article
- Common mental disorders in hematopoietic stem cell transplant patients: a scoping review.Revista brasileira de enfermagem · 2023Article
- Effect of Early Nutritional Support on Quality of Life by EORTC QLQ-C30 in Allogeneic Hematopoietic Stem Cell Transplantation.Blood cell therapy · 2022Article
- Exercise in allogeneic bone marrow transplantation: a qualitative representation of the patient perspective.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
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- Comparable Outcomes and Health-Related Quality of Life for Severe Aplastic Anemia: Haploidentical Combined With a Single Cord Blood UnitFrontiers in oncology · 2021Article
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- Everyday life following hematopoietic stem cell transplantation: decline in physical symptoms within the first month and change-related predictors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018Article
- Centralized patient-reported outcome data collection in transplantation is feasible and clinically meaningful.Cancer · 2017Article
- Spirituality and the recovery of quality of life following hematopoietic stem cell transplantation.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2015Article
- Quality of life in Arab Muslim cancer survivors following hematopoietic stem cell transplantation: comparison with matched healthy group.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Comparison of seven-day and repeated 24-hour recall of symptoms in the first 100 days after hematopoietic cell transplantation.Journal of pain and symptom management · 2015Observational
- Relationships among symptoms, psychosocial factors, and health-related quality of life in hematopoietic stem cell transplant survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Symptom distress predicts long-term health and well-being in allogeneic stem cell transplantation survivors.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014Article
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Authors and funding
9 authors.
Funding
Abstract
Hematopoietic cell transplantation (HCT) is an intensive treatment for hematologic malignancies that has the potential to cure disease or prolong life, but also to impair quality of life for survivors. Earlier studies have suggested that various factors are associated with physical and mental health after HCT. In this study, we evaluated demographic and clinical factors before and after HCT and selected psychosocial factors after HCT, exploring their association with self-reported physical and mental health. We studied a cohort of 662 survivors at a median of 6.6 years after HCT. Pre-HCT demographic and clinical factors accounted for only a small amount of the variance in physical and mental health post-HCT (3% and 1%, respectively). Adding post-HCT clinical variables to the pre-HCT factors accounted for 32% and 7% of physical and mental outcomes, respectively. When both clinical and psychosocial factors were considered, better physical health post-HCT was associated with younger age, race other than white, higher current family income, currently working or being a student, less severe transplantation experience (ie, not experiencing graft-versus-host disease), fewer current comorbidities, higher Karnofsky status, less social constraint, less social support, and less trait anxiety. This multivariate model accounted for 36% of the variance in physical health, with the psychosocial variables contributing very little. When both clinical and psychosocial factors were considered, better mental health after HCT was associated with more severe transplantation experience, less social constraint, greater spiritual well being, and less trait anxiety. This multivariate model accounted for 56% of the variance in mental health, with the psychosocial factors accounting for most of the variance. These data suggest that clinical factors are explanatory for much of the post-HCT physical health reported by HCT survivors, but very little of self-perceived mental health. These observations provide insight into the identification of factors that can allow recognition of at-risk patients, as well as factors amenable to intervention.
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