Evidence map›Paper›PMID 20683706›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2011

Fragility fractures and the osteoporosis care gap in women: the Canadian Multicentre Osteoporosis Study.

L-A Fraser, G Ioannidis, J D Adachi, L Pickard, S M Kaiser, J Prior, J P Brown, D A Hanley, W P Olszynski, T Anastassiades and 5 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Economic impact and cost-effectiveness of fracture liaison services: a systematic review of the literature.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018
    Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. A novel fracture liaison service using digital health: impact on mortality in hospitalized elderly osteoporotic fracture patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Observational
  7. Article
  8. Article
  9. Article
  10. The treatment gap after major osteoporotic fractures in Denmark 2005-2014: a combined analysis including both prescription-based and hospital-administered anti-osteoporosis medications.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
  11. Article
  12. Preventing hip fractures with multidisciplinary teams: a Canadian perspective.Canadian journal of surgery. Journal canadien de chirurgie · 2021
    Review
  13. The Clinical Impact of Fracture Liaison Services: A Systematic Review.Geriatric orthopaedic surgery & rehabilitation · 2021
    Review
  14. Traumatic fractures in China from 2012 to 2014: a National Survey of 512,187 individuals.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  15. Secular trends in the initiation of therapy in secondary fracture prevention in Europe: a multi-national cohort study including data from Denmark, Catalonia, and the United Kingdom.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2020
    Article
  16. Article
  17. Identification and management of patients at increased risk of osteoporotic fracture: outcomes of an ESCEO expert consensus meeting.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017
    Article
  18. The impact of a standardized order set for the management of non-hip fragility fractures in a Fracture Liaison Service.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  19. Men's health-seeking behaviours regarding bone health after a fragility fracture: a secondary analysis of qualitative data.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

L-A FraserDepartments of Epidemiology and Medicine, Hamilton Health Sciences-Chedoke Site, McMaster University, 1200 Main Street West, Hamilton, ON L8N3Z5, Canada.
G Ioannidis
J D Adachi
L Pickard
S M Kaiser
J Prior
J P Brown
D A Hanley
W P Olszynski
T Anastassiades
S Jamal
R Josse
D Goltzman
A Papaioannou
CaMos Research Group
Hamilton Health Sciences · CAMcMaster University · CAUniversity of Toronto · CADalhousie University · CAMcGill University · CAQueen's University · CAUniversité Laval · CAUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Saskatchewan · CA

Funding

CIHR 88225-1
6 · The paper itself

Abstract

unlabelledCanadian women over 50 years old were studied over a 10-year period to see if those who sustained a fracture (caused by minimal trauma) were receiving the recommended osteoporosis therapy. We found that approximately half of these women were not being treated, indicating a significant care gap in osteoporosis treatment.

introductionPrevalent fragility fracture strongly predicts future fracture. Previous studies have indicated that women with fragility fractures are not receiving the indicated treatment. We aimed to describe post fracture care in Canadian women using a large, population-based prospective cohort that began in 1995-1997.

methodsWe followed 5,566 women over 50 years of age from across Canada over a period of 10 years in the Canadian Multicentre Osteoporosis Study. Information on medication use and incident clinical fragility fractures was obtained during a yearly questionnaire or interview and fractures were confirmed by radiographic/medical reports.

resultsOver the 10-year study period, 42-56% of women with yearly incident clinical fragility fractures were not treated with an osteoporosis medication. During year 1 of the study, 22% of the women who had experienced a fragility fracture were on treatment with a bisphosphonate and 26% were on hormone therapy (HT). We were not able to differentiate HT use for menopause symptoms vs osteoporosis. Use of bisphosphonate therapy increased over time; odds ratio (OR) for use at year 10 compared to use at year 1 was 3.65 (95% confidence interval (CI) 1.83-7.26). In contrast, HT use declined, with an OR of 0.07 (95%CI 0.02-0.24) at year 10 compared to year 1 of the study.

conclusionIn a large population-based cohort study, we found a therapeutic care gap in women with osteoporosis and fragility fractures. Although bisphosphonate therapy usage improved over time, a substantial gap remains.

Indexed as

AgedAged, 80 and overBone DensityBone Density Conservation AgentsCanadaDelivery of Health CareDiphosphonatesEstrogen Replacement TherapyFemaleFractures, SpontaneousGuideline AdherenceHumansMiddle AgedOsteoporosis, PostmenopausalOsteoporotic FracturesPractice Patterns, Physicians'Bone Density Conservation AgentsDiphosphonates

Identifiers

PMID20683706
PMCPMC5101074
OpenAlexW1982202312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.