Evidence map›Paper›PMID 20683670›Full record

ArticleMolecular imaging and biology2011

Detection of hepatic metastases using dual-time-point FDG PET/CT scans in patients with colorectal cancer.

Jeong Won Lee, Seok-Ki Kim, Sang Mi Lee, Seung Hwan Moon, Tae-Sung Kim

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 74 citations in OpenAlex.

  1. Trial
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  7. KSNM60 in Clinical Nuclear Oncology.Nuclear medicine and molecular imaging · 2021
    Review
  8. Current state of oncologicAsia Oceania journal of nuclear medicine & biology · 2021
    Article
  9. Article
  10. Usefulness of respiratory-gated PET acquisition during delayedAsia Oceania journal of nuclear medicine & biology · 2021
    Article
  11. Article
  12. Improving the Prognostic Performance of SUVJournal of clinical medicine · 2020
    Article
  13. Total Body PET: Why, How, What for?IEEE transactions on radiation and plasma medical sciences · 2020
    Article
  14. Article
  15. Article
  16. Elevated tumor-to-liver uptake ratio (TLR) fromEuropean journal of nuclear medicine and molecular imaging · 2017
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Jeong Won LeeDepartment of Nuclear Medicine, Jeju National University Hospital, Jeju, Jeju Special Self-Governing Province, South Korea.
Seok-Ki KimDepartment of Nuclear Medicine, National Cancer Center Research Institute and Hospital, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea. skkim@ncc.re.kr.
Sang Mi LeeDepartment of Nuclear Medicine, National Cancer Center Research Institute and Hospital, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea.
Seung Hwan MoonDepartment of Nuclear Medicine, National Cancer Center Research Institute and Hospital, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea.
Tae-Sung KimDepartment of Nuclear Medicine, National Cancer Center Research Institute and Hospital, 323 Ilsan-ro, Ilsandong-gu, Goyang-si, Gyeonggi-do, 410-769, South Korea.
National Cancer Center · KRJeju National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to determine the most useful parameter of dual-time-point 2-deoxy-2-[¹⁸F]fluoro-D: -glucose positron emission tomography/computed tomography (PET/CT) for detection of hepatic metastases in patients with colorectal cancer. PROCEDURES: Thirty-nine patients had undergone a dual-time-point PET/CT scan and a subsequent histopathological confirmation for a workup of hepatic metastases. Detection rates were compared for visual analysis score, standardized uptake value (SUV), tumor-to-liver uptake ratio (TLR), and percent changes of the SUV and TLR.

resultsOf 91 liver lesions, 86 lesions were confirmed as metastases. The SUV and TLR of metastatic lesions on the delayed images were higher than those on the first scan (p < 0.001). The signal-to-noise ratio of the delayed PET scan was higher than that of the first scan (p < 0.0001). The TLR and SUV of the delayed scan showed the highest detection rates of 92% and 88%, whereas percent changes of SUV and TLR showed the lowest detection rates (51%, 67%). Visual analysis detected 87% on the delayed scan and 77% on the first scan.

conclusionsA delayed scan is more favorable for the detection of hepatic metastases of colorectal cancer, and the TLR on the delayed scan was the most useful parameter.

Indexed as

Fluorodeoxyglucose F18Positron-Emission TomographyTomography, X-Ray ComputedAdultAgedAged, 80 and overColorectal NeoplasmsContrast MediaFemaleHumansLiverLiver NeoplasmsMaleMiddle AgedROC CurveTime FactorsContrast MediaFluorodeoxyglucose F18

Identifiers

PMID20683670
OpenAlexW2069001013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.