ArticleJournal of neurology2011
Sensory neuropathy in patients with cryoglobulin negative hepatitis-C infection.
Article in Journal of neurology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Pain-related evoked potentials with concentric surface electrodes in patients and healthy subjects: a systematic review.Brain structure & function · 2023Pooled it
- Treatment for cryoglobulinemic and non-cryoglobulinemic peripheral neuropathy associated with hepatitis C virus infection.The Cochrane database of systematic reviews · 2014Pooled it
- Anodal transcutaneous spinal direct current stimulation influences the amplitude of pain-related evoked potentials in healthy subjects.Scientific reports · 2023Trial
- Evaluation of Quantitative and Selective Sensory Fiber Dysfunction in Patients with Cirrhosis.Current neurovascular research · 2024Article
- Peripheral neuropathy after viral eradication with direct-acting antivirals in chronic HCV hepatitis: A prospective study.Liver international : official journal of the International Association for the Study of the Liver · 2021Article
- [Neurological complications of hepatitis C infections].Der Nervenarzt · 2021Review
- Myocardial ischaemia reperfusion injury and cardioprotection in the presence of sensory neuropathy: Therapeutic options.British journal of pharmacology · 2020Review
- A deceiving case of paraplegia.Internal and emergency medicine · 2020Article
- Article
- Hepatitis C virus and neurological damage.World journal of hepatology · 2016Review
- Screening for Electrophysiological Abnormalities in Chronic Hepatitis C Infection: Peripheral Neuropathy and Optic Neuropathy.Noro psikiyatri arsivi · 2016Article
- Amplitudes of Pain-Related Evoked Potentials Are Useful to Detect Small Fiber Involvement in Painful Mixed Fiber Neuropathies in Addition to Quantitative Sensory Testing - An Electrophysiological Study.Frontiers in neurology · 2015Article
- Extrahepatic immune related manifestations in chronic hepatitis C virus infection.World journal of gastroenterology · 2014Review
- Clinical, neurophysiological, and skin biopsy findings in peripheral neuropathy associated with hepatitis C virus-related cryoglobulinemia.Journal of neurology · 2014Article
- Idiopathic small fiber neuropathy: phenotype, etiologies, and the search for fabry disease.Journal of clinical neurology (Seoul, Korea) · 2014Article
- [Clinical application of pain-related evoked potentials].Schmerz (Berlin, Germany) · 2012Review
- HCV-related nervous system disorders.Clinical & developmental immunology · 2012Review
- [Is fibromyalgia a viral disease?].Zeitschrift fur Rheumatologie · 2011Article
- Conditioned pain modulation and nociception measured by pain-related evoked potentials in patients with polyneuropathy.Frontiers in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is growing evidence that hepatitis-C virus (HCV) infection might cause peripheral neuropathy. We aimed to investigate the prevalence, clinical and electrophysiological features of sensory neuropathy in patients with cryoglobulin negative HCV infection. We studied 46 consecutive cryoglobulin negative HCV positive patients (24 of them with and 22 without neuropathic symptoms, NS) and compared to 28 age and gender matched controls. In all patients and controls, clinical neuropathy symptom (NSS) and neuropathy deficit scores (NDS) were assessed and standard nerve conduction velocity (SNCV) and pain related-evoked potentials (PREP) were recorded. Both, SNCV and PREP were abnormal in 13 NS positive patients (13/46, 28%). Abnormal PREP but normal SNCV were found in 5 (5/46, 11%) NS positive and in 2 NS negative patients (2/46, 4%). PREP abnormalities correlated positive with both clinical neuropathy scores (NSS r=0.62; p<0.001; NDS r=0.57; p<0.001), but not with the duration of the disease, current viral load, or the virus subtype. PREP abnormalities were more frequent (16/33, 48.5%) in HCV patients treated with interferon than in therapy naïve patients (4/13, 30.8%); the difference was, however, not significant. In our present study (1) all virus subtypes are capable of inducing neuropathy, (2) no differences were found between interferon therapy and treatment naive patients, (3) the prevalence of peripheral sensory neuropathy including small sensory fibers (20/46, 43.5%) is higher than previously reported and (4) we found that detection of HCV associated neuropathy depends on the evaluation method.
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