ArticleEuropean radiology2011
Positive contrast visualization of SPIO-labeled pancreatic islets using echo-dephased steady-state free precession.
Article in European radiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- Upconverting Nanoparticles for Bimodal Luminescence and Magnetic Resonance Imaging of Langerhans Islets.Small science · 2026Article
- Boosting the velocity detection limit of 3D single-cell tracking time-lapse MRI by balanced SSFP imaging.Magnetic resonance in medicine · 2025Article
- Water-soluble fluorinated copolymers as highly sensitiveMaterials today. Bio · 2025Article
- Iron-based compounds coordinated with phospho-polymers as biocompatible probes for dualScientific reports · 2024Article
- Article
- Detection of iron-labeled single cells by MR imaging based on intermolecular double quantum coherences at 14 T.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveMRI has recently been introduced as a promising method of monitoring the transplanted pancreatic islets labelled with superparamagnetic iron oxide (SPIO). However, the traditional [Formula: see text]-weighted approach frequently yields ambiguous results because of the negative contrast of the SPIO particles on the background of other body components. This obstacle could be overcome with the use of a novel method known as echo-dephased steady state free precession (SSFP), generating positive contrast in the presence of paramagnetic material.
methodsIn phantoms, we achieved exact localisation and clear positive contrast visualisation of human SPIO labelled islets. Using the proposed method we demonstrated the ability to detect even a single pancreatic islet against a homogeneous background.
resultsIn vivo experiments in rats confirmed reliable and accurate localisation of transplanted SPIO labelled islets.
conclusionThe echo-dephased SSFP technique could successfully visualise SPIO-labelled human and rat pancreatic islets yielding a positive contrast.
Indexed as
Identifiers
20683599What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.