Evidence map›Paper›PMID 20683346›Full record

ArticleJournal of investigative medicine : the official publication of the American Federation for Clinical Research2010

Using a type 1 collagen-based system to understand cell-scaffold interactions and to deliver chimeric collagen-binding growth factors for vascular tissue engineering.

Yonggang Pang, Howard P Greisler

Abstract readConsensus Statement
In one paragraph

Article in Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Self-organizing tissue-engineered constructs in collagen hydrogels.Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada · 2012
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yonggang PangDepartment of Surgery, Loyola University Medical Center, Maywood, IL 60153, USA.
Howard P Greisler

Funding

GROWTH FACTOR MEDIATION OF HEALING OF VASCULAR GRAFTSR01HL041272 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI GREISLER, HOWARD P · 1988 to 2006
$2.0M
AFMR-Translational Medical Research Symposia SeriesR13RR023236 · NCRR · AMERICAN FEDERATION FOR MEDICAL RESEARCH · PI ZUCKER, DEBORAH R · 2006 to 2010
$263k
NCRR NIH HHS R13 RR023236NHLBI NIH HHS R01 HL041272NHLBI NIH HHS R01-HL41272
6 · The paper itself

Abstract

Vascular tissue engineering should provide more biocompatible and functional conduits than synthetic vascular grafts. Understanding cell-scaffold interactions and developing an efficient delivery system for growth factors and other biomolecules to control the signaling between the cells and the scaffold are fundamental issues in a wide range of tissue engineering research fields. Type 1 collagen is a natural scaffold extensively used in vascular tissue engineering and is a widely used vehicle in biomolecule delivery. In this article, we will discuss type 1 collagen as a vascular tissue engineering scaffold, describe strategies for elucidating the interaction between cells and type 1 collagen scaffolds using various imaging techniques, and summarize our work on the development of a chimeric collagen-binding growth factor-based local delivery system.

Indexed as

Blood Vessel ProsthesisTissue ScaffoldsAnimalsCollagen Type IDrug Delivery SystemsHumansIntercellular Signaling Peptides and ProteinsProtein BindingRecombinant Fusion ProteinsCollagen Type IIntercellular Signaling Peptides and ProteinsRecombinant Fusion Proteins

Identifiers

PMID20683346
PMCPMC2950018

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.