Evidence map›Paper›PMID 20682332›Full record

ArticleNeuroscience2010

Cloning and distribution of Ca2+-activated K+ channels in lobster Panulirus interruptus.

Q Ouyang, V Patel, J Vanderburgh, R M Harris-Warrick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Q OuyangDepartment of Neurobiology and Behavior, Cornell University, Ithaca,NY 14853, USA. qingouyang2000@gmail.com
V Patel
J Vanderburgh
R M Harris-Warrick
Cornell University · US

Funding

NEUROTRANSMITTERS, NEUROMODULATORS &MOTOR SYSTEMSR01NS017323 · NINDS · CORNELL UNIVERSITY ITHACA · PI HARRIS-WARRICK, RONALD M · 1985 to 2017
$3.3M
Neurotransmitters, Neuromodulators and Motor SystemsR37NS017323 · NINDS · CORNELL UNIVERSITY · PI HARRIS-WARRICK, RONALD M · 2006 to 2012
$2.9M
NINDS NIH HHS R01 NS017323NINDS NIH HHS R01 NS17323NINDS NIH HHS R37 NS017323
6 · The paper itself

Abstract

Large conductance Ca(2+)-activated potassium (BK) channels play important roles in controlling neuronal excitability. We cloned the PISlo gene encoding BK channels from the spiny lobster, Panulirus interruptus. This gene shows 81-98% sequence identity to Slo genes previously found in other organisms. We isolated a number of splice variants of the PISlo cDNA within Panulirus interruptus nervous tissue. Sequence analysis indicated that there are at least seven alternative splice sites in PISlo, each with multiple alternative segments. Using immunohistochemistry, we found that the PISlo proteins are distributed in the synaptic neuropil, axon and soma of stomatogastric ganglion (STG) neurons.

Indexed as

Alternative SplicingAmino Acid SequenceAnimalsCloning, MolecularGanglia, InvertebrateLarge-Conductance Calcium-Activated Potassium ChannelsMolecular Sequence DataNeuropilPalinuridaeProtein IsoformsLarge-Conductance Calcium-Activated Potassium ChannelsProtein Isoforms

Identifiers

PMID20682332
PMCPMC2940416
OpenAlexW1970227132

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.