ArticleAlcohol (Fayetteville, N.Y.)2010
Cortical perfusion in alcohol-dependent individuals during short-term abstinence: relationships to resumption of hazardous drinking after treatment.
Article in Alcohol (Fayetteville, N.Y.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03842670 (Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neurocognitive and Neurobehavioral Mechanisms of Change Following Psychological
Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Structural and functional brain recovery in individuals with substance use disorders during abstinence: A review of longitudinal neuroimaging studies.Drug and alcohol dependence · 2022Pooled it
- Salience network structural integrity predicts executive impairment in alcohol use disorders.Scientific reports · 2018Trial
- Effects of a GABA-ergic medication combination and initial alcohol withdrawal severity on cue-elicited brain activation among treatment-seeking alcoholics.Psychopharmacology · 2013Trial
- Interspecies and regional variability of alcohol action on large cerebral arteries: regulation by KCNMB1 proteins.American journal of physiology. Regulatory, integrative and comparative physiology · 2023Article
- Cerebral Blood Flow in the Salience Network of Individuals with Alcohol Use Disorder.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Using machine learning to predict heavy drinking during outpatient alcohol treatment.Alcoholism, clinical and experimental research · 2022Article
- Attenuated cerebral blood flow in frontolimbic and insular cortices in Alcohol Use Disorder: Relation to working memory.Journal of psychiatric research · 2021Article
- Brain-behavior relations and effects of aging and common comorbidities in alcohol use disorder: A review.Neuropsychology · 2019Review
- The Relationship Between Regional Cerebral Blood Flow Estimates and Alcohol Problems at 5-Year Follow-Up: The Role of Level of Response.Alcoholism, clinical and experimental research · 2019Article
- Regional cerebral blood flow in opiate dependence relates to substance use and neuropsychological performance.Addiction biology · 2018Article
- Toward biomarkers of the addicted human brain: Using neuroimaging to predict relapse and sustained abstinence in substance use disorder.Progress in neuro-psychopharmacology & biological psychiatry · 2018Review
- Regional brain volume changes in alcohol-dependent individuals during early abstinence: associations with relapse following treatment.Addiction biology · 2017Article
- Brain perfusion in polysubstance users: relationship to substance and tobacco use, cognition, and self-regulation.Drug and alcohol dependence · 2015Article
- Brain proton magnetic resonance spectroscopy of alcohol use disorders.Handbook of clinical neurology · 2014Review
- Profiles of impaired, spared, and recovered neuropsychologic processes in alcoholism.Handbook of clinical neurology · 2014Review
- Resting-state synchrony during early alcohol abstinence can predict subsequent relapse.Cerebral cortex (New York, N.Y. : 1991) · 2013Article
- Adolescents' fMRI activation to a response inhibition task predicts future substance use.Addictive behaviors · 2013Article
- The use of brain imaging to elucidate neural circuit changes in cocaine addiction.Substance abuse and rehabilitation · 2012Article
- Effects of alcohol intoxication and gender on cerebral perfusion: an arterial spin labeling study.Alcohol (Fayetteville, N.Y.) · 2011Article
- Brain morphology at entry into treatment for alcohol dependence is related to relapse propensity.Biological psychiatry · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Relapse to hazardous levels of alcohol consumption after treatment for alcohol use disorders is common. Investigation of the neurobiological correlates of resumption of hazardous drinking is necessary to clarify the mechanisms contributing to relapse. Fifty-seven treatment-seeking alcohol-dependent participants (ALC) completed arterial spin labeling perfusion MRI of the frontal and parietal gray matter (GM) at 7+/-3 days of abstinence (baseline). ALC participants were restudied after 35+/-11 days of abstinence (assessment point 2: AP2). Twenty-eight nonsmoking, light-drinking control participants (nsLD) from the community were studied with perfusion MRI. ALC participants were followed over 12 months after baseline study and were classified as abstainers (no alcohol consumption; n=19) and resumers (any alcohol consumption; n=38) at follow-up. Cross-sectional and longitudinal perfusion was compared in abstainers, resumers, and nsLD. At baseline, resumers demonstrated significantly lower frontal and parietal GM perfusion than nsLD and abstainers. Abstainers and nsLD were not different on frontal or parietal GM perfusion. No significant longitudinal perfusion changes were observed in abstainers and resumers. At AP2, resumers showed significantly lower frontal GM perfusion than nsLD and abstainers, whereas no group differences were observed for parietal GM. Abstainers and nsLD were not different on frontal GM perfusion. The significantly decreased frontal GM perfusion in resumers compared with both abstainers and nsLD across the assessment interval suggests premorbid and/or acquired neurobiological abnormalities of the frontal GM in resumers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.