ArticleProceedings of the National Academy of Sciences of the United States of America1991
Phosphatidate-dependent protein phosphorylation.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed, 149 citations in OpenAlex.
- Mammalian phospholipase D: Function, and therapeutics.Progress in lipid research · 2020Review
- Dysregulated Lipid Metabolism and Its Role in α-Synucleinopathy in Parkinson's Disease.Frontiers in neuroscience · 2019Review
- Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway.American journal of physiology. Cell physiology · 2010Article
- Kinesins in the Arabidopsis genome: a comparative analysis among eukaryotes.BMC genomics · 2001Article
- Phospholipase D-derived phosphatidic acid is involved in the activation of the CD11b/CD18 integrin in human eosinophils.The Biochemical journal · 1999Article
- Relocalization of phospholipase D activity mediates membrane formation during meiosis.The Journal of cell biology · 1998Article
- Increased phospholipase D activity in human breast cancer.Journal of cancer research and clinical oncology · 1997Article
- A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Article
- Evidence and nature of a novel thiol-oxidase in human platelets.Molecular and cellular biochemistry · 1996Article
- Characterization of Saccharomyces cerevisiae deficient in expression of phospholipase D.The Biochemical journal · 1996Article
- G Protein Activation Stimulates Phospholipase D Signaling in Plants.The Plant cell · 1995Article
- Cell-free activation of neutrophil NADPH oxidase by a phosphatidic acid-regulated protein kinase.Proceedings of the National Academy of Sciences of the United States of America · 1995Article
- Time-course changes in content and fatty acid composition of phosphatidic acid from rat thymocytes during concanavalin A stimulation.The Biochemical journal · 1995Article
- Leukotriene B4 stimulation of an early elevation of phosphatidic acid mass in human neutrophils.Lipids · 1995Article
- Characterization of a regulated form of phospholipase D in the yeast Saccharomyces cerevisiae.The Biochemical journal · 1995Article
- Phosphatidic acid signaling mediates lung cytokine expression and lung inflammatory injury after hemorrhage in mice.The Journal of experimental medicine · 1995Article
- Phosphatidic acid activation of protein kinase C-zeta overexpressed in COS cells: comparison with other protein kinase C isotypes and other acidic lipids.The Biochemical journal · 1994Article
- Guanosine 5'-[gamma-thio]triphosphate induces membrane localization of cytosol-independent phospholipase D activity in a cell-free system from U937 promonocytic leucocytes.The Biochemical journal · 1994Article
- Membrane-associated diacylglycerol kinase activity is increased by noradrenaline, but not by angiotensin II, in arterial smooth muscle.The Biochemical journal · 1994Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Phosphatidate-dependent protein phosphorylation was observed in soluble extracts from rat liver, brain, lung, and testis. The phosphorylation was stimulated by free Ca2+ in the range of 360-800 nM. Incubation mixtures containing phosphatidate provided markedly different profiles of protein phosphorylation from those with phosphatidylserine plus 1,2-diolein. Phosphatidate-dependent phosphorylation of a 30-kDa protein in the soluble fraction from heart was also observed. This phosphorylation did not require Ca2+. Soluble fractions from liver, testis, brain, and lung phosphorylated the 30-kDa heart protein in a phosphatidate-dependent Ca(2+)-independent manner. We propose that part of the action of phosphatidate in cells may be mediated by a protein kinase(s).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.