Evidence map›Paper›PMID 2068100›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1991

Molecular cloning of matrin F/G: A DNA binding protein of the nuclear matrix that contains putative zinc finger motifs.

D J Hakes, R Berezney

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
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  6. Isolation of a multispecific organic anion and cardiac glycoside transporter from rat brain.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
  7. Article
  8. The choroid plexus epithelium is the site of the organic anion transport protein in the brain.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
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  11. A novel, conserved gene of the rat that is developmentally regulated in the testis.Mammalian genome : official journal of the International Mammalian Genome Society · 1994
    Article
  12. Expression cloning of a rat liver Na(+)-independent organic anion transporter.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nuclear matrins: identification of the major nuclear matrix proteins.Proceedings of the National Academy of Sciences of the United States of America · 1991
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

D J HakesDepartment of Biological Sciences, State University of New York, Buffalo 14260.
R Berezney
University at Buffalo, State University of New York · US

Funding

NUCLEAR MATRIX STRUCTURES AND GENOMIC FUNCTIONR01GM023922 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BEREZNEY, RONALD · 1985 to 2002
$1.1M
NIGMS NIH HHS GM-23922
6 · The paper itself

Abstract

We have isolated a 2.7-kilobase rat liver cDNA clone that contains the entire 544-amino acid coding sequence for matrin F/G. This protein has previously been localized to the internal, fibrogranular areas of the nuclear matrix and shown to bind to DNA on nitrocellulose blots. The predicted amino acid sequence from the coding region of this cDNA shows that this protein contains approximately 50% hydrophobic amino acids with secondary structure predictions suggesting a large percentage of beta-sheet regions. No significant homologies were found with any other known proteins, including the nuclear lamins. The predicted amino acid sequence was also searched for DNA binding motifs. Two putative zinc finger motifs were found. In addition, a 7-mer palindromic sequence (Ser-Ser-Thr-Asn-Thr-Ser-Ser) was discovered within one of these zinc finger DNA binding regions. A possible regulatory role for this element is discussed.

Indexed as

AntiportersAmino Acid SequenceAnimalsBase SequenceBinding SitesDNADNA-Binding ProteinsGene LibraryLiverMolecular Sequence DataNuclear MatrixOrganic Anion TransportersProtein ConformationRatsRestriction MappingZinc FingersAntiportersDNADNA-Binding ProteinsOrganic Anion TransportersSlco2a1 protein, rat

Identifiers

PMID2068100
PMCPMC52047
OpenAlexW2070718713

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.