ArticleCurrent microbiology2011
Identification of differentially expressed genes in Flammulina velutipes with anti-tyrosinase activity.
Article in Current microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed, 6 citations in OpenAlex.
- Prediction of Key Candidate Genes for Platinum Resistance in Ovarian Cancer.International journal of general medicine · 2021Article
- NEAT1 regulates pancreatic cancer cell growth, invasion and migration though mircroRNA-335-5p/c-met axis.American journal of cancer research · 2016Article
- Golden Needle Mushroom: A Culinary Medicine with Evidenced-Based Biological Activities and Health Promoting Properties.Frontiers in pharmacology · 2016Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It was previously shown that fruiting bodies of the mushroom, Flammulina velutipes, exert anti-tyrosinase activity by producing a triacylglycerol characterized as 1',3'-dilinolenoyl-2'-linoleoylglycerol (LnLLn). In this study, we provide evidence that the mycelia of F. velutipes grown on glucose, but not on glycerol, exhibit anti-tyrosinase activity. To identify genes possibly involved in the process of expressing anti-tyrosinase activity in F. velutipes, a reverse transcription-polymerase chain reaction (RT-PCR) method that involves annealing control primers (ACPs) was employed. Using 120 ACPs, a total of 84 differentially expressed genes (DEGs) in F. velutipes mycelia with anti-tyrosinase activity were cloned and sequenced. Basic Local Alignment Search Tool (BLAST) searches revealed that 72 of the genes have known sequence homology. Of these, three genes involved in the synthesis and modification of fatty acids were selected and further quantified by real-time RT-PCR. These genes involved in fatty acid-biosynthetic processes can be potential candidates for further studies related to the development of a new anti-browning agent.
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Registered trials
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