Evidence map›Paper›PMID 20679581›Full record

ReviewCirculation2010

Stem cell therapy for vascular regeneration: adult, embryonic, and induced pluripotent stem cells.

Nicholas J Leeper, Arwen L Hunter, John P Cooke

Registry-linked trialAbstract readReview
In one paragraph

Review in Circulation, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04466007 (Multicenter, Randomized, Dose-search, Parallel, Double-blind, and Placebo-controlled Clinical Trial to Evaluate the Safety and Efficacy of Intramuscular Administration of Allogeneic Adipose Tissue Adult Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia Without Possibility of Revascularization), which is not on this map. Cited by 106 papers.

0numbers the graph read from it
0cells of the map it votes in
106citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04466007 phase2completednot on this mapstarted 2021, after this paper: background citation

Multicenter, Randomized, Dose-search, Parallel, Double-blind, and Placebo-controlled Clinical Trial to Evaluate the Safety and Efficacy of Intramuscular Administration of Allogeneic Adipose Tissue Adult Mesenchymal Stem Cells in Diabetic Patients With Critical Limb Ischemia Without Possibility of Revascularization

TypeinterventionalSponsorInstituto de Investigación Sanitaria de la Fundación Jiménez DíazRan2021 to 2024Enrolled90ConditionsLimb Ischemia, Diabetic FootArmsHigh dose allogeneic mesenchymal stromal cells, Low dose allogeneic mesenchymal stromal cells, Placebos
3 · Its place in the literature

Who cites it

106 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Characterization and angiogenic potential of CD146Stem cell research & therapy · 2024
    Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

46 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nicholas J LeeperDivision of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, Calif 94305, USA.
Arwen L Hunter
John P Cooke

Funding

Basic and Translational Research of iPSC-Based hematologic and Vascular TherapiesU01HL099775 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI FRIEDMAN, ALAN D · 2009 to 2015
$8.4M
Basic and Translational Research iPSC-based hematologic and vascular therapiesU01HL100397 · NHLBI · STANFORD UNIVERSITY · PI COOKE, JOHN P · 2009 to 2015
$7.4M
Genetic Determinants of PADR01HL075774 · NHLBI · STANFORD UNIVERSITY · PI COOKE, JOHN P · 2003 to 2007
$5.0M
Stanford Career Development in Vascular MedicineK12HL087746 · NHLBI · STANFORD UNIVERSITY · PI DALMAN, RONALD L · 2007 to 2012
$3.5M
NCE-based strategy for nuclear reprogramming and regenerative medicineRC2HL103400 · NHLBI · STANFORD UNIVERSITY · PI COOKE, JOHN P · 2009 to 2010
$2.7M
NHLBI NIH HHS 1U01HL100397NHLBI NIH HHS K12 HL087746NHLBI NIH HHS R01 HL075774NHLBI NIH HHS R01 HL-75774NHLBI NIH HHS RC2 HL103400NHLBI NIH HHS RC2HL103400NHLBI NIH HHS U01HL099775NHLBI NIH HHS U01 HL100397
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adult Stem CellsEmbryonic Stem CellsHumansNeovascularization, PhysiologicPluripotent Stem CellsRegenerationStem Cell TransplantationVascular Diseases

Identifiers

PMID20679581
PMCPMC2920605

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.