ArticlePediatrics2010
Early medical and behavioral characteristics of NICU infants later classified with ASD.
Article in Pediatrics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Auditory brainstem response in infants and children with autism spectrum disorder: A meta-analysis of wave V.Autism research : official journal of the International Society for Autism Research · 2018Pooled it
- Infant Attention to Eyes Versus Mouth Varies With Mouth Movement Speed, Family History of Autism and Language Development.Journal of autism and developmental disorders · 2026Article
- Prematurity and autism: a dose-response relationship across gestational age.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Transgenerational Effects and Heritability of Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorder.International journal of molecular sciences · 2025Article
- Sensory-movement underpinnings of lifelong neurodivergence: getting a grip on autism.Frontiers in integrative neuroscience · 2025Article
- Exploring early life social and executive function development in infants and risk for autism: a prospective cohort study protocol of NICU graduates and infants at risk for cerebral palsy.BMC psychiatry · 2024Article
- Newborn Auditory Brainstem Responses in Children with Developmental Disabilities.Journal of autism and developmental disorders · 2023Article
- Mismatch Negativity and Auditory Brain Stem Response in Children with Autism Spectrum Disorders and Language Disorders.Journal of multidisciplinary healthcare · 2023Article
- Multiview child motor development dataset for AI-driven assessment of child development.GigaScience · 2022Article
- Social and non-social sensory responsivity in toddlers at high-risk for autism spectrum disorder.Autism research : official journal of the International Society for Autism Research · 2021Article
- Infant's Behaviour Checklist for low birth weight infants and later neurodevelopmental outcome.Scientific reports · 2021Observational
- Kinematics and observer-animator kinematic similarity predict mental state attribution from Heider-Simmel style animations.Scientific reports · 2021Article
- Hyper-Reactivity to Salience Limits Social Interaction Among Infants Born Pre-term and Infant Siblings of Children With ASD.Frontiers in psychiatry · 2021Article
- Association of maternal sleep before and during pregnancy with preterm birth and early infant sleep and temperament.Scientific reports · 2020Article
- Early Motor Development Predicts Clinical Outcomes of Siblings at High-Risk for Autism: Insight from an Innovative Motion-Tracking Technology.Brain sciences · 2020Article
- A Comparison of Children Born Preterm and Full-Term on the Autism Spectrum in a Prospective Community Sample.Frontiers in neurology · 2020Article
- Autism spectrum disorder is associated with gut microbiota disorder in children.BMC pediatrics · 2019Article
- Functional Connectome of the Fetal Brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Early features of autism spectrum disorder: a cross-sectional study.Italian journal of pediatrics · 2019Article
- A longitudinal study of parent-reported sensory responsiveness in toddlers at-risk for autism.Journal of child psychology and psychiatry, and allied disciplines · 2019Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectivesRecent evidence suggests higher prevalence of autism spectrum disorder (ASD) in NICU graduates. This aim of this study was to identify retrospectively early behaviors found more frequently in NICU infants who went on to develop ASD.
methodsTwenty-eight NICU graduates who later received a diagnosis of ASD were compared with 2169 other NICU graduates recruited from 1994 to 2005. They differed in gender, gestational age, and birth cohort. These characteristics were used to draw a matched control sample (n=112) to determine which, if any, early behaviors discriminated subsequent ASD diagnosis. Behavioral testing at targeted ages (adjusted for gestation) included the Rapid Neonatal Neurobehavioral Assessment (hospital discharge, 1 month), Arousal-Modulated Attention (hospital discharge, 1 and 4 months), and Bayley Scales of Infant Development (multiple times, 4-25 months).
resultsAt 1 month, children with ASD but not control children had persistent neurobehavioral abnormalities and higher incidences of asymmetric visual tracking and arm tone deficits. At 4 months, children with ASD had continued visual preference for higher amounts of stimulation than did control children, behaving more like newborns. Unlike control children, children with ASD had declining mental and motor performance by 7 to 10 months, resembling infants with severe central nervous system involvement.
conclusionsDifferences in specific behavior domains between NICU graduates who later receive a diagnosis of ASD and matched NICU control children may be identified in early infancy. Studies with this cohort may provide insights to help understand and detect early disabilities, including ASD.
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