ArticleBiotechnology for biofuels2010
Improving simultaneous saccharification and co-fermentation of pretreated wheat straw using both enzyme and substrate feeding.
Article in Biotechnology for biofuels, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 86 citations in OpenAlex.
- Biorefining Process of Carbohydrate Feedstock (Agricultural Onion Waste) to Acetic Acid.ACS omega · 2019Article
- Agro-industrial waste recycling by Trichosporon fermentans: conversion of waste sweetpotato vines alone into lipid.Environmental science and pollution research international · 2018Article
- Adaptive Response and Tolerance to Acetic Acid inFrontiers in microbiology · 2018Review
- Enhancement of ethanol production from green liquor-ethanol-pretreated sugarcane bagasse by glucose-xylose cofermentation at high solid loadings with mixedBiotechnology for biofuels · 2017Article
- Article
- Bioreactors for lignocellulose conversion into fermentable sugars for production of high added value products.Applied microbiology and biotechnology · 2016Review
- Process design of SSCF for ethanol production from steam-pretreated, acetic-acid-impregnated wheat straw.Biotechnology for biofuels · 2016Article
- From wheat straw to bioethanol: integrative analysis of a separate hydrolysis and co-fermentation process with implemented enzyme production.Biotechnology for biofuels · 2015Article
- Conversion of cellulosic materials into glycolipid biosurfactants, mannosylerythritol lipids, by Pseudozyma spp. under SHF and SSF processes.Microbial cell factories · 2014Article
- Process intensification through microbial strain evolution: mixed glucose-xylose fermentation in wheat straw hydrolyzates by three generations of recombinant Saccharomyces cerevisiae.Biotechnology for biofuels · 2014Article
- Combining the effects of process design and pH for improved xylose conversion in high solid ethanol production from Arundo donax.AMB Express · 2014Article
- SSF of steam-pretreated wheat straw with the addition of saccharified or fermented wheat meal in integrated bioethanol production.Biotechnology for biofuels · 2013Article
- High gravity and high cell density mitigate some of the fermentation inhibitory effects of softwood hydrolysates.AMB Express · 2013Article
- Competition between pentoses and glucose during uptake and catabolism in recombinant Saccharomyces cerevisiae.Biotechnology for biofuels · 2012Article
- Separate hydrolysis and co-fermentation for improved xylose utilization in integrated ethanol production from wheat meal and wheat straw.Biotechnology for biofuels · 2012Article
- Simultaneous saccharification and cofermentation of lignocellulosic residues from commercial furfural production and corn kernels using different nutrient media.Biotechnology for biofuels · 2011Article
- Low temperature lignocellulose pretreatment: effects and interactions of pretreatment pH are critical for maximizing enzymatic monosaccharide yields from wheat straw.Biotechnology for biofuels · 2011Article
- A mutated xylose reductase increases bioethanol production more than a glucose/xylose facilitator in simultaneous fermentation and co-fermentation of wheat straw.AMB Express · 2011Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSimultaneous saccharification and co-fermentation (SSCF) has been recognized as a feasible option for ethanol production from xylose-rich lignocellulosic materials. To reach high ethanol concentration in the broth, a high content of water-insoluble solids (WIS) is needed, which creates mixing problems and, furthermore, may decrease xylose uptake. Feeding of substrate has already been proven to give a higher xylose conversion than a batch SSCF. In the current work, enzyme feeding, in addition to substrate feeding, was investigated as a means of enabling a higher WIS content with a high xylose conversion in SSCF of a xylose-rich material. A recombinant xylose-fermenting strain of Saccharomyces cerevisiae (TMB3400) was used for this purpose in fed-batch SSCF experiments of steam-pretreated wheat straw.
resultsBy using both enzyme and substrate feeding, the xylose conversion in SSCF could be increased from 40% to 50% in comparison to substrate feeding only. In addition, by this design of the feeding strategy, it was possible to process a WIS content corresponding to 11% in SSCF and obtain an ethanol yield on fermentable sugars of 0.35 g g-1.
conclusionA combination of enzyme and substrate feeding was shown to enhance xylose uptake by yeast and increase overall ethanol yield in SSCF. This is conceptually important for the design of novel SSCF processes aiming at high-ethanol titers. Substrate feeding prevents viscosity from becoming too high and thereby allows a higher total amount of WIS to be added in the process. The enzyme feeding, furthermore, enables keeping the glucose concentration low, which kinetically favors xylose uptake and results in a higher xylose conversion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.