ArticleRheumatology international2012
Relation of plasma total homocysteine, folate and vitamin B12 levels to bone mineral density in Moroccan healthy postmenopausal women.
Article in Rheumatology international, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 4 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 4 syntheses or guidelines pooled it, 45 citations in OpenAlex.
- Prevalence of postmenopausal osteoporosis in Morocco: a systematic review and meta-analysis.Archives of osteoporosis · 2024Pooled it
- Genetically predicted circulating serum homocysteine levels on osteoporosis: a two-sample mendelian randomization study.Scientific reports · 2023Pooled it
- Correlation of oxidative stress-related biomarkers with postmenopausal osteoporosis: a systematic review and meta-analysis.Archives of osteoporosis · 2021Pooled it
- Oxidative Stress-Related Biomarkers in Postmenopausal Osteoporosis: A Systematic Review and Meta-Analyses.Disease markers · 2016Pooled it
- The role of B-vitamin intake, B-vitamin-rich dietary patterns, the B-vitamin deficiency index in bone mineral density among school-aged children.Pediatric research · 2026Article
- Article
- Role of vitamins beyond vitamin DInternational journal of molecular medicine · 2024Review
- The correlation between vitamin B12 and folate levels and bone mineral density among the Saudi population in a primary care setting.Journal of family medicine and primary care · 2023Article
- Associations between Plasma Folate and Vitamin BNutrients · 2022Observational
- Exosomal lncRNA-H19 promotes osteogenesis and angiogenesis through mediating Angpt1/Tie2-NO signaling in CBS-heterozygous mice.Theranostics · 2021Article
- Association between plasma total homocysteine level within normal range and bone mineral density in adults.Journal of orthopaedic surgery and research · 2020Article
- Article
- Bariatric Surgery: Bad to the Bone, Part 1.Integrative medicine (Encinitas, Calif.) · 2016Review
- B-vitamin status and bone mineral density and risk of lumbar osteoporosis in older females in the United States.The American journal of clinical nutrition · 2015Article
- The Role of B-Vitamins in Bone Health and Disease in Older Adults.Current osteoporosis reports · 2015Review
- Vitamin B12, folate, homocysteine, and bone health in adults and elderly people: a systematic review with meta-analyses.Journal of nutrition and metabolism · 2013Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To test whether in Moroccan healthy postmenopausal women, levels of plasma total homocysteine (tHcy), folate, and vitamin B12 are related to BMD. A total of 188 volunteer postmenopausal women were recruited from our blood taking center between April 2008 and December 2008. Each subject completed a standardized questionnaire designed to document putative risk factors of osteoporosis. Bone mineral density was determined by a Lunar Prodigy Vision DXA system, and blood samples for plasma tHcy, folate, vitamin B12, and serum parathyroid hormone (PTH) were taken. Comparison between women with osteoporosis, osteopenia and normal BMD showed that the osteoporotic women were significantly older, had lower weight and height than the women of the other groups. Plasma tHcy was significantly higher in the osteoporotic group. Levels of tHcy were inversely related to BMD at the lumbar spine, at the total hip and plasma vitamin B12 and positively related to age and creatinine. Multiple regression analysis showed that age and BMI were the main predictors of BMD at the lumbar spine, whereas the main predictors of BMD at the total hip were age, BMI, plasma tHcy, and plasma vitamin B(12). tHcy and vitamin B12 are independent risk factors for osteoporosis in Moroccan healthy postmenopausal women.
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Registered trials
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