ReviewRheumatology international2011
Current, new and future treatments of osteoporosis.
Review in Rheumatology international, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Disease Systems Analysis of Bone Mineral Density and Bone Turnover Markers in Response to Alendronate, Placebo, and Washout in Postmenopausal Women.CPT: pharmacometrics & systems pharmacology · 2016Trial
- Baseline characteristics and bone mineral density changes associated with lower fracture risk in osteoporosis: a retrospective cohort study.Rheumatology international · 2026Observational
- Monitoring fracture risk during antiosteoporotic therapy: a retrospective cohort study.Rheumatology international · 2025Observational
- Canola Protein Hydrolysates Show Osteogenic Activity in MC3T3-E1 Cells.Journal of food science · 2025Article
- Osteogenic differentiation of mesenchymal stem cells in cell-laden culture of self-assembling peptide hydrogels.OpenNano · 2025Article
- Effect of the body mass index, basal metabolic rate, and body fat on the radiofrequency echographic multi-spectrometry (REMS)-based bone mineral density and fracture risk: a cross-sectional study.Rheumatology international · 2023Article
- An observational study of the radiofrequency echographic multi-spectrometry (REMS)-based fragility score of the lumbar spine and total fracture risk at 5 years in women.Rheumatology international · 2023Observational
- Aging of Skeletal Stem Cells.Advances in geriatric medicine and research · 2022Article
- Novel positive allosteric modulators of AJournal of enzyme inhibition and medicinal chemistry · 2021Article
- Calcium Sulphate/Hydroxyapatite Carrier for Bone Formation in the Femoral Neck of Osteoporotic Rats.Tissue engineering. Part A · 2018Article
- The effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (HMG-CoA), on the prevention of osteoporosis in ovariectomized rabbits.Journal of bone and mineral metabolism · 2017Article
- New horizons in treatment of osteoporosis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2017Review
- Increased treatment persistence and its determinants in women with osteoporosis with prior fracture compared to those without fracture.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Article
- The functional mechanism of simvastatin in experimental osteoporosis.Journal of bone and mineral metabolism · 2016Article
- Zoledronic acid in children with osteogenesis imperfecta and Bruck syndrome: a 2-year prospective observational study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016Observational
- Denosumab Related Osteonecrosis of the Jaw with Spontaneous Necrosis of the Soft Palate: Report of a Life Threatening Case.Case reports in dentistry · 2016Article
- Sulfuretin induces osteoblast differentiation through activation of TGF-β signaling.Molecular and cellular biochemistry · 2015Article
- Effects of OsteoKing on osteoporotic rabbits.Molecular medicine reports · 2015Article
- The Tissue-Selective Estrogen Complex: A Review of Current Evidence.Rheumatology and therapy · 2015Review
- The influence of pregnancy and lactation on maternal bone health: a systematic review.Journal of family & reproductive health · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoporosis as a common chronic disease is challenging human health. Although different therapeutic options are routinely used for prevention/treatment of osteoporosis, their side effects and benefits are under question. Increasing our knowledge about signaling pathways in bone and osteocytes as well as osteoblasts and osteoclasts will help us in designing new therapeutic modalities for osteoporosis. In the present study, all new therapeutic measures of osteoporosis have been reviewed. For this purpose, search engines like Pubmed, Web of Science, Scopus, Google Scholar were searched and all relevant articles were found. The study was limited to the year 1998-2010. Bisphosphonates are the cornerstone of osteoporosis treatment, but there are not enough relevant studies that investigated their equivalencies in comparison with each other or the other medications. Therefore, medication selection is empirical and subjective. Furthermore, no eminent study has compared certain combinations. There are new hopes for treatment of osteoporosis, which are more specific with less harm. Our results show that new and emerging therapies are more potent and target specified which more individualize osteoporosis treatment; however, more investigations on their safety and efficacy in comparison with current medications are highly recommended.
Indexed as
Identifiers
20676643What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.