ReviewThe Canadian veterinary journal = La revue veterinaire canadienne2010
Spinal cord injury I: A synopsis of the basic science.
Review in The Canadian veterinary journal = La revue veterinaire canadienne, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Combined laser-activated SVF and PRP remodeled spinal sclerosis via activation of Olig-2, MBP, and neurotrophic factors and inhibition of BAX and GFAP.Scientific reports · 2024Article
- Acacetin alleviates neuroinflammation and oxidative stress injury via the Nrf2/HO-1 pathway in a mouse model of spinal cord injury.Translational neuroscience · 2022Article
- Characterization of microglia/macrophage phenotypes in the spinal cord following intervertebral disc herniation.Frontiers in veterinary science · 2022Article
- Current Insights Into the Pathology of Canine Intervertebral Disc Extrusion-Induced Spinal Cord Injury.Frontiers in veterinary science · 2020Review
- "Acute onset tetraplegia associated with immune-mediated thrombocytopenia and suspected secondary intraspinal hemorrhage in a dog".Clinical case reports · 2019Article
- Necrosulfonamide Ameliorates Neurological Impairment in Spinal Cord Injury by Improving Antioxidative Capacity.Frontiers in pharmacology · 2019Article
- Role of hypoxia‑inducible factor‑1α in autophagic cell death in microglial cells induced by hypoxia.Molecular medicine reports · 2017Article
- Methylprednisolone exerts neuroprotective effects by regulating autophagy and apoptosis.Neural regeneration research · 2016Article
- Gross anatomical study of the nerve supply of genitourinary structures in female mongrel hound dogs.Anatomia, histologia, embryologia · 2015Article
- Stem cells in canine spinal cord injury--promise for regenerative therapy in a large animal model of human disease.Stem cell reviews and reports · 2015Review
- Pilot study: bone marrow stem cells as a treatment for dogs with chronic spinal cord injury.Regenerative medicine research · 2014Article
- Influences of HIF-lα on Bax/Bcl-2 and VEGF expressions in rats with spinal cord injury.International journal of clinical and experimental pathology · 2013Article
- Potential role of stem cells in severe spinal cord injury: current perspectives and clinical data.Stem cells and cloning : advances and applications · 2012Review
- Cannabidiol-treated rats exhibited higher motor score after cryogenic spinal cord injury.Neurotoxicity research · 2012Article
- Mesenchymal stem cell graft improves recovery after spinal cord injury in adult rats through neurotrophic and pro-angiogenic actions.PloS one · 2012Article
- Neural tissue engineering using embryonic and induced pluripotent stem cells.Stem cell research & therapy · 2011Review
- overcoming dogmatic barrier in neurosciences research: an applause for annals of neurosciences paradigm.Annals of neurosciences · 2011Article
- Article
- Dystocia and cesarean section in a free-ranging ocelot (Open veterinary journalArticle
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Substantial knowledge has been gained in the pathological findings following naturally occurring spinal cord injury (SCI) in dogs and cats. The molecular mechanisms involved in failure of neural regeneration within the central nervous system, potential therapeutics including cellular transplantation therapy, neural plasticity, and prognostic indicators of recovery from SCI have been studied. This 2-part review summarizes 1) basic science perspectives regarding treating and curing spinal cord injury, 2) recent studies that shed light on prognosis and recovery from SCI, 3) current thinking regarding standards of care for dogs with SCI, 4) experimental approaches in the laboratory setting, and 5) current clinical trials being conducted in veterinary medicine. Part I presents timely information on the pathophysiology of spinal cord injury, challenges associated with promoting regeneration of neurons of the central nervous system, and experimental approaches aimed at developing treatments for spinal cord injury.
Indexed as
Identifiers
20676289PMC2857426What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.