ArticleNature chemical biology2010
A copper-containing oxidase catalyzes C-nitrosation in nitrosobenzamide biosynthesis.
Article in Nature chemical biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 49 citations in OpenAlex.
- Structural insights intoInorganic chemistry frontiers · 2026Article
- Identification of an Activity Selector for the Nitroso-Forming Activity in Bacterial Type-III Copper Enzymes.Angewandte Chemie (International ed. in English) · 2025Article
- Classification of polyphenol oxidases shows ancient gene duplication leading to two distinct enzyme types.iScience · 2025Article
- Coupled Binuclear Copper Sites in Biology: An Experimentally-Calibrated Computational Perspective.Coordination chemistry reviews · 2025Article
- Tyrosinases: a family of copper-containing metalloenzymes.Chemtexts · 2024Article
- New mechanistic insights into coupled binuclear copper monooxygenases from the recent elucidation of the ternary intermediate of tyrosinase.FEBS letters · 2023Review
- Elucidation of the tyrosinase/OProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Structure and Candidate Biosynthetic Gene Cluster of a Manumycin-Type Metabolite fromJournal of natural products · 2022Review
- Pigments of aminophenoxazinones and viridomycins produced by termite-associatedFrontiers in microbiology · 2022Article
- Article
- Synthetic Fe/Cu Complexes: Toward Understanding Heme-Copper Oxidase Structure and Function.Chemical reviews · 2018Review
- Heteroatom-Heteroatom Bond Formation in Natural Product Biosynthesis.Chemical reviews · 2017Review
- Activation of dioxygen by copper metalloproteins and insights from model complexes.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2017Review
- A nitrous acid biosynthetic pathway for diazo group formation in bacteria.Nature chemical biology · 2016Article
- The Cremeomycin Biosynthetic Gene Cluster Encodes a Pathway for Diazo Formation.Chembiochem : a European journal of chemical biology · 2015Article
- Copper active sites in biology.Chemical reviews · 2014Review
- Structure/function correlations among coupled binuclear copper proteins through spectroscopic and reactivity studies of NspF.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Metalloenzymes: Natural product nitrosation.Nature chemical biology · 2010Article
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5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although C-nitroso aromatic compounds have several bioactivities of medicinal interest, the biosynthetic enzymes involved in C-nitrosation have remained unknown until now. Here, we report the entire biosynthesis pathway of 4-hydroxy-3-nitrosobenzamide in Streptomyces murayamaensis, in which a tyrosinase-like copper-containing monooxygenase is responsible for the C-nitrosation. This finding indicates diverse catalytic functions of tyrosinase-like copper-containing monooxygenases in nature.
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