ArticleApplied and environmental microbiology2010
Enhanced production of a plant monoterpene by overexpression of the 3-hydroxy-3-methylglutaryl coenzyme A reductase catalytic domain in Saccharomyces cerevisiae.
Article in Applied and environmental microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Advances in the biosynthesis and metabolic engineering of rare ginsenosides.Applied microbiology and biotechnology · 2023Review
- Multi-Level Optimization and Strategies in Microbial Biotransformation of Nature Products.Molecules (Basel, Switzerland) · 2023Review
- Transcriptome sequencing reveals terpene biosynthesis pathway genes accounting for volatile terpene of tree peony.Planta · 2021Article
- Isopentenol Utilization Pathway for the Production of Linalool in Escherichia coli Using an Improved Bacterial Linalool/Nerolidol Synthase.Chembiochem : a European journal of chemical biology · 2021Article
- Fermentative production of Vitamin E tocotrienols in Saccharomyces cerevisiae under cold-shock-triggered temperature control.Nature communications · 2020Article
- Recent Advances on Feasible Strategies for Monoterpenoid Production inFrontiers in bioengineering and biotechnology · 2020Review
- Production of the Fragrance Geraniol in Peroxisomes of a Product-Tolerant Baker's Yeast.Frontiers in bioengineering and biotechnology · 2020Article
- Engineering the oleaginous yeast Yarrowia lipolytica to produce the aroma compound β-ionone.Microbial cell factories · 2018Article
- Review
- Transcriptome Sequencing Analysis Reveals a Difference in Monoterpene Biosynthesis between ScentedFrontiers in plant science · 2017Article
- Recombinant expression of a GH12 β-glucanase carrying its own signal peptide from Stachybotrys atra in yeast and filamentous fungi.World journal of microbiology & biotechnology · 2016Article
- Lycopene overproduction in Saccharomyces cerevisiae through combining pathway engineering with host engineering.Microbial cell factories · 2016Article
- A 'Plug and Play' Platform for the Production of Diverse Monoterpene Hydrocarbon Scaffolds inChemistrySelect · 2016Article
- De novo production of six key grape aroma monoterpenes by a geraniol synthase-engineered S. cerevisiae wine strain.Microbial cell factories · 2015Article
- Engineered biosynthesis of natural products in heterologous hosts.Chemical Society reviews · 2015Review
- Evolutionary Engineering Improves Tolerance for Replacement Jet Fuels in Saccharomyces cerevisiae.Applied and environmental microbiology · 2015Article
- Article
- Development of bio-based fine chemical production through synthetic bioengineering.Microbial cell factories · 2014Article
- Improving industrial yeast strains: exploiting natural and artificial diversity.FEMS microbiology reviews · 2014Review
- Protein design for pathway engineering.Journal of structural biology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Linalool production was evaluated in different Saccharomyces cerevisiae strains expressing the Clarkia breweri linalool synthase gene (LIS). The wine strain T(73) was shown to produce higher levels of linalool than conventional laboratory strains (i.e., almost three times the amount). The performance of this strain was further enhanced by manipulating the endogenous mevalonate (MVA) pathway: deregulated overexpression of the rate-limiting 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) doubled linalool production. In a haploid laboratory strain, engineering of this key step also improved linalool yield.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.