Central sensitization versus synaptic long-term potentiation (LTP): a critical comment.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

14 citing papers in PubMed.

1. Neural correlates of heterotopic facilitation induced after high frequency electrical stimulation of nociceptive pathways.Molecular pain · 2011
   Trial
2. Mapping the neuroethological signatures of pain, analgesia, and recovery in mice.Neuron · 2023
   Article
3. Spinal cord stimulation in chronic pain: evidence and theory for mechanisms of action.Bioelectronic medicine · 2019
   Article
4. Interaction between NMDA Receptor- and Endocannabinoid-Mediated Modulation of Nociceptive Synapses.Scientific reports · 2019
   Article
5. From Mechanism to Cure: Renewing the Goal to Eliminate the Disease of Pain.Pain medicine (Malden, Mass.) · 2018
   Review
6. Comparative biology of pain: What invertebrates can tell us about how nociception works.Journal of neurophysiology · 2017
   Review
7. Commonalities between pain and memory mechanisms and their meaning for understanding chronic pain.Progress in molecular biology and translational science · 2015
   Review
8. Roles of phosphotase 2A in nociceptive signal processing.Molecular pain · 2013
   Review
9. Involvement of EphB1 receptors signalling in models of inflammatory and neuropathic pain.PloS one · 2013
   Article
10. Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain.Pain · 2012
    Article
11. Self-injurious behaviour in intellectual disability syndromes: evidence for aberrant pain signalling as a contributing factor.Journal of intellectual disability research : JIDR · 2012
    Review
12. Fragile X mental retardation protein (FMRP) and the spinal sensory system.Results and problems in cell differentiation · 2012
    Article
13. Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011
    Article
14. Inflammatory pain unmasks heterosynaptic facilitation in lamina I neurokinin 1 receptor-expressing neurons in rat spinal cord.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011
    Article

Corrections and comments

• Commented on by
  Synaptic plasticity and central sensitization: author reply.2010
• Comment on
  Central sensitization: a generator of pain hypersensitivity by central neural plasticity.2009

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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