Evidence map›Paper›PMID 20673807›Full record

ReviewMicrobes and infection2010

Modulation of the host immune response by cowpox virus.

Dina Alzhanova, Klaus Früh

Abstract readReview
In one paragraph

Review in Microbes and infection, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Biology of Variola Virus.Advances in experimental medicine and biology · 2024
    Review
  3. Review
  4. Review
  5. Article
  6. The evolving epidemiology of monkeypox virus.Cytokine & growth factor reviews · 2022
    Review
  7. Article
  8. Article
  9. TNF Decoy Receptors Encoded by Poxviruses.Pathogens (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Cowpox virus protein CPXV012 eludes CTLs by blocking ATP binding to TAP.Journal of immunology (Baltimore, Md. : 1950) · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dina AlzhanovaVaccine and Gene Therapy Institute, Oregon Health and Science University, NW 185th Ave., Beaverton, OR 97006, USA.
Klaus Früh

Funding

Mechanisms of T cell Escape by OrthopoxvirusesR21AI077048 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI FRUH, KLAUS J · 2007 to 2008
$419k
NIAID NIH HHS R21 AI077048
6 · The paper itself

Abstract

Cowpox virus, a zoonotic poxvirus endemic to Eurasia, infects a large number of host species which makes its eradication impossible. The elimination of world-wide smallpox vaccination programs renders the human population increasingly susceptible to infection by orthopoxviruses resulting in a growing number of zoonotic infections including CPXV transmitted from domestic animals to humans. The ability of CPXV to infect a wide range of mammalian host is likely due to the fact that, among the orthopoxviruses, CPXV encodes the most complete set of open reading frames expected to encode immunomodulatory proteins. This renders CPXV particularly interesting for studying poxviral strategies to evade and counteract the host immune responses.

Indexed as

Immune EvasionImmune ToleranceAnimalsCowpoxCowpox virusHumansViral ProteinsVirulence FactorsZoonosesViral ProteinsVirulence Factors

Identifiers

PMID20673807
PMCPMC3500136

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.