Evidence map›Paper›PMID 20671873›Full record

ReviewBlood transfusion = Trasfusione del sangue2010

Prothrombin complex concentrates: an update.

Massimo Franchini, Giuseppe Lippi

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Blood transfusion = Trasfusione del sangue, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04244981 (Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery, Compared With Fresh Frozen Plasma), which is not on this map. Cited by 71 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04244981 phase4terminatednot on this mapstarted 2023, after this paper: background citation

Efficacy of Prothrombin Complex Concentrate Reducing Perioperative Blood Loss in Cardiac Surgery, Compared With Fresh Frozen Plasma: Study Protocol for a Non-inferiority, Randomized Controlled Trial

TypeinterventionalSponsorSHI JiaRan2023 to 2025Enrolled476ConditionsValvular Heart SurgeryArmsProthrombin Complex Concentrate, Human, Fresh Frozen Plasma
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Review
  12. Observational
  13. Article
  14. Patient blood management in pregnancy, the peripartum, and the postpartum period.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Massimo FranchiniServizio di Immunoematologia e Trasfusione, Azienda Ospedaliero-Universitaria di Parma, Italy. mfranchini@ao.pr.it
Giuseppe Lippi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood Coagulation FactorsBlood CoagulationChemistry, PharmaceuticalHemorrhageHumansBlood Coagulation Factorsprothrombin complex concentratesover-anticoagulation reversalPCCprothrombin complex concentratethrombosis

Identifiers

PMID20671873
PMCPMC2906185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.