Evidence map›Paper›PMID 20669057›Full record

ReviewStem cell reviews and reports2010

Pluripotent stem cells: origin, maintenance and induction.

Maria P De Miguel, Sherezade Fuentes-Julián, Yago Alcaina

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 75 citations in OpenAlex.

  1. Review
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  4. Positron emission tomography probes for stem cell monitoring: a review.American journal of translational research · 2024
    Review
  5. Stem cells and pain.World journal of stem cells · 2023
    Review
  6. Article
  7. Stem Cell Therapies for Epidermolysis Bullosa Treatment.Bioengineering (Basel, Switzerland) · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria P De MiguelCell Engineering Laboratory, La Paz Hospital Research Institute, IdiPAZ, Paseo Castellana 261, Madrid, 28046, Spain. mariapdemiguel@gmail.com
Sherezade Fuentes-Julián
Yago Alcaina
Hospital La Paz Institute for Health Research · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pluripotency is defined as the potential of a cell to differentiate into cells of the three germ layers: endoderm, mesoderm and ectoderm. In vivo, the presence of pluripotent stem cells is transient during the very early embryo. However, immortal cell lines with the same properties can be obtained in vitro and grown indefinitely in laboratories under specific conditions. These cells can be induced to differentiate into all the cell types of the organism through different assays, thereby proving their functional pluripotency. This review focuses on the pluripotent stem cells of mammals, giving special attention to the comparison between mouse and human. In particular, embryonic stem cells, epiblast-derived stem cells, primordial germ cells, embryonic germ cells, very small embryonic-like cells and induced pluripotent stem cells will be compared in terms of the following: in vivo specification and location; surface and intracellular markers; in vitro dependence on growth factors; signal transduction pathways; epigenetic characteristics; and pluripotency genes and functional assays.

Indexed as

AnimalsCell DifferentiationEmbryonic Stem CellsHumansInduced Pluripotent Stem CellsMesenchymal Stem CellsModels, BiologicalPluripotent Stem Cells

Identifiers

PMID20669057
OpenAlexW2159906006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.