Evidence map›Paper›PMID 20668934›Full record

ArticleVeterinary research communications2010

Differential expression of Toll-like receptor mRNA in White Leghorn and indigenous chicken of India.

Kannaki T Ramasamy, Maddula R Reddy, Dhanutha N Raveendranathan, Shanmugam Murugesan, Rudra N Chatterjee, Rajkumar Ullengala, Santosh Haunshi

Abstract read
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Article in Veterinary research communications, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

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  8. Illumina Next Generation Sequencing for the Analysis ofFrontiers in veterinary science · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kannaki T RamasamyProject Directorate on Poultry, Hyderabad, 500030,, Andhra Pradesh, India. trkannaki@gmail.com
Maddula R Reddy
Dhanutha N Raveendranathan
Shanmugam Murugesan
Rudra N Chatterjee
Rajkumar Ullengala
Santosh Haunshi
Directorate of Poultry Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present experiment, the expression profile of Toll-like receptor mRNA in indigenous and pure line chickens was studied. The expression of TLR3, TLR4, TLR5 and TLR7 were quantified in heterophils of Aseel, Kadaknath, Naked neck, Dwarf and White Leghorn lines by Quantitative Real-time PCR. White Leghorns expressed significantly (P < 0.01) higher levels of TLR3 mRNA compared to other lines. TLR4 and TLR5 mRNA were significantly highly expressed in Kadaknath line. Among the TLRs investigated TLR5 was more expressed in all lines studied. TLR7 was highly expressed in indigenous chicken Aseel and Kadaknath than other lines. Dwarf chicken expressed significantly (P < 0.01) lower levels of all TLRs investigated. On the basis of the present study we conclude that the differential expression of TLR mRNA in the heterophils of indigenous and other chicken breeds might contribute to their variable disease resistance/susceptibility.

Indexed as

AnimalsChickensGene Expression RegulationIndiaPolymerase Chain ReactionRNA, MessengerToll-Like ReceptorsRNA, MessengerToll-Like Receptors

Identifiers

PMID20668934
OpenAlexW2053297217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.