Evidence map›Paper›PMID 20668281›Full record

ArticlePsychosomatic medicine2010

Recurrent major depression predicts progression of coronary calcification in healthy women: Study of Women's Health Across the Nation.

Karen A Matthews, Yue-Fang Chang, Kim Sutton-Tyrrell, Daniel Edmundowicz, Joyce T Bromberger

Open access · greenAbstract readComparative Study
In one paragraph

Article in Psychosomatic medicine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

  1. Pooled it
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  10. Interaction between smoking and depressive symptoms with subclinical heart disease in the Coronary Artery Risk Development in Young Adults (CARDIA) study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2017
    Article
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  17. Progression of coronary artery calcification in black and white women: do the stresses and rewards of multiple roles matter?Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2012
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Karen A MatthewsDepartment of Psychiatry, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, USA. matthewska@upmc.edu
Yue-Fang Chang
Kim Sutton-Tyrrell
Daniel Edmundowicz
Joyce T Bromberger
National Institutes of Health · USNational Institute of Nursing Research · USNational Institute on Aging · US

Funding

WOMENS HEALTH ACROSS THE NATION--COORDINATING CENTERU01AG012553 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROOKS, MARIA MORI · 1994 to 2019
$37.7M
WOMENS HEALTH ACROSS THE NATION--ENDOCRINE LABU01AG012495 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MCCONNELL, DANIEL S · 1994 to 2018
$18.8M
WOMENS HEALTH ACROSS THE NATION--PITTSBURGHU01AG012546 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MATTHEWS, KAREN · 1994 to 2019
$16.2M
WOMENS HEALTH ACROSS THE NATION--UCDAVISU01AG012554 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI GOLD, ELLEN B. · 1994 to 2019
$14.5M
WOMENS HEALTH ACROSS THE NATION--UCLAU01AG012539 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI GREENDALE, GAIL A · 1994 to 2018
$13.7M
THE STUDY OF WOMEN'S HEALTH ACROSS THE NATION-MICHIGANU01NR004061 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HARLOW, SIOBAN D · 1994 to 2018
$12.9M
WOMENS HEALTH ACROSS THE NATION--CHICAGOU01AG012505 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI KRAVITZ, HOWARD M · 1994 to 2019
$11.9M
WOMENS HEALTH ACROSS THE NATION--MASSACHUSETTS GENERAL HU01AG012531 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI FINKELSTEIN, JOEL S · 1994 to 2019
$10.7M
Women's Health Across the Nation-New Jersey SiteU01AG012535 · NIA · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI DERBY, CAROL A. · 1994 to 2019
$9.2M
Menopause Depression and AgingR01MH059689 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BROMBERGER, JOYCE T · 1999 to 2010
$2.9M
NIA NIH HHS AG012495NIA NIH HHS AG012505NIA NIH HHS AG012531NIA NIH HHS AG012535NIA NIH HHS AG012539NIA NIH HHS AG012546NIA NIH HHS AG012553NIA NIH HHS AG012554NIA NIH HHS U01 AG012495NIA NIH HHS U01 AG012505NIA NIH HHS U01 AG012531NIA NIH HHS U01 AG012535NIA NIH HHS U01 AG012539NIA NIH HHS U01 AG012546NIA NIH HHS U01 AG012553NIA NIH HHS U01 AG012554NIMH NIH HHS MH059689NIMH NIH HHS R01 MH059689NINR NIH HHS NR004061NINR NIH HHS U01 NR004061
6 · The paper itself

Abstract

objectiveTo test the hypothesis that African American and white women with recurrent major depression would show greater progression of coronary artery calcification (CAC) than would women with a single episode or no episode of major depression. Depressive symptoms and major depression are risk factors for clinical coronary heart disease (CHD) among CHD patients and among healthy individuals. It is less clear whether depression is related to the progression of atherosclerosis before the onset of CHD events.

designLongitudinal cohort study.

methodsA total of 149 middle-aged healthy women (n = 113 white and 36 African American) who reported no heart disease, stroke, or diabetes were enrolled simultaneously in two ancillary studies of the Study of Women's Health Across the Nation at the Pittsburgh site: the Mental Health Study and the Study of Women's Health Across the Nation Heart Study. These women were administered psychiatric interviews annually and CAC computed tomography measures on two occasions approximately 2¼ years apart.

resultsWomen who had recurrent major depression (n = 33) had greater progression of CAC (logged difference scores) than did women with a single or no episodes, b = 0.09 (0.04), p = .01. The other significant covariates were body mass index, systolic blood pressure, initial CAC, and time between scans. Stratified analyses showed that the effect was obtained in those women who had any CAC on the first examination.

conclusionsRecurrent major depression may be a risk factor for progression of atherosclerosis, especially in those who have at least some initial calcification. Women with a history of depression may be candidates for aggressive cardiovascular risk factor prevention therapy.

Indexed as

AdultBlood PressureBody Mass IndexCalcinosisComorbidityCoronary AngiographyCoronary Artery DiseaseCoronary VesselsDiagnostic and Statistical Manual of Mental DisordersDisease ProgressionFemaleHumansLongitudinal StudiesMajor Depressive DisorderMiddle AgedProbability

Identifiers

PMID20668281
PMCPMC2950893
OpenAlexW2081819850

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.