ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2010
Coalescence and fragmentation of cortical networks during focal seizures.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 106 papers, 1 of them a synthesis that pooled it.
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Who cites it
106 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Network reorganization of anterograde thalamic connectivity during non-periodic patterned deep brain stimulation.iScience · 2026Article
- Large-Scale Synchronization Dynamics During Epileptic Seizures: A Patient-Independent EEG Network Analysis.Entropy (Basel, Switzerland) · 2026Article
- Thalamic organization differentially contributes to clinical conditions in epilepsy.Communications medicine · 2026Article
- Distinct Spectral and Directional Thalamocortical Network Dynamics Define Focal Seizure Evolution.medRxiv : the preprint server for health sciences · 2026Article
- White matter signals reflect information transmission between brain regions during seizures.Brain : a journal of neurology · 2026Article
- Static and dynamic intracerebral signal analysis reveals protective networks against seizures in drug-resistant focal epilepsy.Brain communications · 2026Article
- Spatiotemporal Brain Dynamics During Cyclic Seizures of Super-Refractory Status Epilepticus.European journal of neurology · 2025Article
- Individualized morphological covariation network aberrance associated with seizure relapse after antiseizure medication withdrawal.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Preictal connectivity dynamics: Exploring inflow and outflow in iEEG networks.Frontiers in network physiology · 2025Article
- Abnormal Topological Organization of Structural Covariance Networks in Patients with Temporal Lobe Epilepsy Comorbid Sleep Disorder.Brain sciences · 2023Article
- Distinguishing between different percolation regimes in noisy dynamic networks with an application to epileptic seizures.PLoS computational biology · 2023Article
- Article
- Abnormal brain functional network dynamics in sleep-related hypermotor epilepsy.CNS neuroscience & therapeutics · 2023Article
- Chronic intracranial EEG recordings and interictal spike rate reveal multiscale temporal modulations in seizure states.Brain communications · 2023Article
- The time-evolving epileptic brain network: concepts, definitions, accomplishments, perspectives.Frontiers in network physiology · 2023Review
- A framework For brain atlases: Lessons from seizure dynamics.NeuroImage · 2022Article
- Fluctuations in EEG band power at subject-specific timescales over minutes to days explain changes in seizure evolutions.Human brain mapping · 2022Article
- Seizure classification with selected frequency bands and EEG montages: a Natural Language Processing approach.Brain informatics · 2022Article
- FKN/CX3CR1 axis facilitates migraine-Like behaviour by activating thalamic-cortical network microglia in status epilepticus model rats.The journal of headache and pain · 2022Article
46 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Epileptic seizures reflect a pathological brain state characterized by specific clinical and electrical manifestations. The proposed mechanisms are heterogeneous but united by the supposition that epileptic activity is hypersynchronous across multiple scales, yet principled and quantitative analyses of seizure dynamics across space and throughout the entire ictal period are rare. To more completely explore spatiotemporal interactions during seizures, we examined electrocorticogram data from a population of male and female human patients with epilepsy and from these data constructed dynamic network representations using statistically robust measures. We found that these networks evolved through a distinct topological progression during the seizure. Surprisingly, the overall synchronization changed only weakly, whereas the topology changed dramatically in organization. A large subnetwork dominated the network architecture at seizure onset and preceding termination but, between, fractured into smaller groups. Common network characteristics appeared consistently for a population of subjects, and, for each subject, similar networks appeared from seizure to seizure. These results suggest that, at the macroscopic spatial scale, epilepsy is not so much a manifestation of hypersynchrony but instead of network reorganization.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.