Evidence map›Paper›PMID 20667436›Full record

ReviewCurrent opinion in cell biology2010

Growth and division--not a one-way road.

Alexi I Goranov, Angelika Amon

Open access · bronzeAbstract readReview
In one paragraph

Review in Current opinion in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Spatial and Translational Regulation of Exocyst Subunits by Cell Cycle in Budding Yeast.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
  8. Article
  9. Article
  10. Prognostic Significance of Cyclins A2, B1, D1, and E1 andAnalytical cellular pathology (Amsterdam) · 2018
    Article
  11. Polarized Exocytosis.Cold Spring Harbor perspectives in biology · 2017
    Review
  12. Article
  13. Article
  14. The expression of CDK1 is associated with proliferation and can be a prognostic factor in epithelial ovarian cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  15. Small but Mighty: Cell Size and Bacteria.Cold Spring Harbor perspectives in biology · 2015
    Review
  16. Article
  17. Review
  18. The clinical significance of CDK1 expression in oral squamous cell carcinoma.Medicina oral, patologia oral y cirugia bucal · 2015
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexi I GoranovDavid H. Koch Institute for Integrative Cancer Research and Howard Hughes Medical Institute, Massachusetts Institute of Technology, E17-233, 40 Ames Street, Cambridge, MA 02139, USA.
Angelika Amon
Howard Hughes Medical Institute · US

Funding

TRANS-NETWORK PROJECTSU54CA143874 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI CHAKRABORTY, ARUP K. · 2009 to 2013
$15.1M
Howard Hughes Medical InstituteNCI NIH HHS 1-U54-CA143874-01NCI NIH HHS U54 CA143874
6 · The paper itself

Abstract

Maintaining cell size homeostasis and regulating cell size in response to changing conditions is a fundamental property of organisms. Here we examine the recent advances in our understanding of the interplay between accumulation of mass (growth) and the progression through the cell cycle (proliferation), the coordination of which determines the size of cells. It is well established that growth affects cell division (reviewed in Jorgensen and Tyers, 2004). This review will focus on the reverse, less well-defined relationship-how cell cycle progression affects growth. We will summarize findings that indicate that growth is not constant during the cell cycle and discuss the surprising possibility that cyclin-dependent kinases (CDKs) inhibit growth.

Indexed as

ActinsCell CycleCell DivisionCell Growth ProcessesCell PolarityCell ProliferationCell SizeSaccharomyces cerevisiaeSchizosaccharomycesActins

Identifiers

PMID20667436
PMCPMC2988085
OpenAlexW1997839679

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.