ArticleElectrophoresis2010
Integration of on-chip peristaltic pumps and injection valves with microchip electrophoresis and electrochemical detection.
Article in Electrophoresis, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- Use of 3D printing to integrate microchip electrophoresis with amperometric detection.Analytical and bioanalytical chemistry · 2024Article
- PolyJet-Based 3D Printing against Micromolds to Produce Channel Structures for Microchip Electrophoresis.ACS omega · 2022Article
- Systematic characterization of cleanroom-free fabricated macrovalves, demonstrating pumps and mixers for automated fluid handling tuned for organ-on-chip applications.Microsystems & nanoengineering · 2022Article
- Fully 3D printed fluidic devices with integrated valves and pumps for flow injection analysis.Analytical methods : advancing methods and applications · 2021Article
- Critical Considerations for the Design of Multi-Organ Microphysiological Systems (MPS).Frontiers in cell and developmental biology · 2021Review
- Development of an on-chip sample injection system with a 6-port valve incorporated in a microchip.RSC advances · 2020Article
- Integration of High-Resolution Radiation Detector for Hybrid Microchip Electrophoresis.Analytical chemistry · 2020Article
- Instrumented Microphysiological Systems for Real-Time Measurement and Manipulation of Cellular Electrochemical Processes.iScience · 2019Review
- Microfluidic device using a gold pillar array and integrated electrodes for on-chip endothelial cell immobilization, direct RBC contact, and amperometric detection of nitric oxide.Electroanalysis · 2019Article
- Integrating 3D Cell Culture of PC12 Cells with Microchip-Based Electrochemical Detection.Analytical methods : advancing methods and applications · 2019Article
- Use of 3D Printing and Modular Microfluidics to Integrate Cell Culture, Injections and Electrochemical Analysis.Analytical methods : advancing methods and applications · 2018Article
- Enhanced Microchip Electrophoresis Separations Combined with Electrochemical Detection Utilizing a Capillary Embedded in Polystyrene.Analytical methods : advancing methods and applications · 2018Article
- Automated microfluidic devices integrating solid-phase extraction, fluorescent labeling, and microchip electrophoresis for preterm birth biomarker analysis.Analytical and bioanalytical chemistry · 2018Article
- Recent Progress toward Microfluidic Quality Control Testing of Radiopharmaceuticals.Micromachines · 2017Review
- Novel volumetric method for highly repeatable injection in microchip electrophoresis.Analytica chimica acta · 2017Article
- Monitoring cell secretions on microfluidic chips using solid-phase extraction with mass spectrometry.Analytical and bioanalytical chemistry · 2017Article
- Microchip-based electrochemical detection using a 3-D printed wall-jet electrode device.The Analyst · 2016Article
- Pressure-actuated microfluidic devices for electrophoretic separation of pre-term birth biomarkers.Analytical and bioanalytical chemistry · 2016Article
- Integrated hybrid polystyrene-polydimethylsiloxane device for monitoring cellular release with microchip electrophoresis and electrochemical detection.Analytical methods : advancing methods and applications · 2015Article
- Getting started with open-hardware: development and control of microfluidic devices.Electrophoresis · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
A microfluidic approach that integrates peristaltic pumping from an on-chip reservoir with injection valves, microchip electrophoresis and electrochemical detection is described. Fabrication and operation of both the peristaltic pumps and injection valves were optimized to ensure efficient pumping and discrete injections. The final device uses the peristaltic pumps to continuously direct sample from a reservoir containing a mixture of analytes to injection valves that are coupled with microchip electrophoresis and amperometric detection. The separation and direct detection of dopamine and norepinephrine were possible with this approach and the utility of the device was demonstrated by monitoring the stimulated release of these neurotransmitters from a layer of cells introduced into the microchip. It is also shown that this pumping/reservoir approach can be expanded to multiple reservoirs and pumps, where one reservoir can be addressed individually or multiple reservoirs sampled simultaneously.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.