Evidence map›Paper›PMID 20664718›Full record

ArticleStatistica Sinica2009

An Information Matrix Prior for Bayesian Analysis in Generalized Linear Models with High Dimensional Data.

Mayetri Gupta, Joseph G Ibrahim

Abstract read
In one paragraph

Article in Statistica Sinica, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mayetri GuptaDepartment of Biostatistics, Boston University, MA 02118, U.S.A. Email: gupta@bu.edu ; ;
Joseph G Ibrahim

Funding

Bayesian Approaches to Model Selection for Survival DataR01GM070335 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI IBRAHIM, JOSEPH G · 2003 to 2019
$4.0M
Bayesian methods for elucidating transcription regulatory mechanisms in eukaryotiR03HG004946 · NHGRI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GUPTA, MAYETRI · 2008 to 2009
$163k
NHGRI NIH HHS R03 HG004946NIGMS NIH HHS R01 GM070335
6 · The paper itself

Abstract

An important challenge in analyzing high dimensional data in regression settings is that of facing a situation in which the number of covariates p in the model greatly exceeds the sample size n (sometimes termed the "p > n" problem). In this article, we develop a novel specification for a general class of prior distributions, called Information Matrix (IM) priors, for high-dimensional generalized linear models. The priors are first developed for settings in which p < n, and then extended to the p > n case by defining a ridge parameter in the prior construction, leading to the Information Matrix Ridge (IMR) prior. The IM and IMR priors are based on a broad generalization of Zellner's g-prior for Gaussian linear models. Various theoretical properties of the prior and implied posterior are derived including existence of the prior and posterior moment generating functions, tail behavior, as well as connections to Gaussian priors and Jeffreys' prior. Several simulation studies and an application to a nucleosomal positioning data set demonstrate its advantages over Gaussian, as well as g-priors, in high dimensional settings.

Identifiers

PMID20664718
PMCPMC2909687

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.