Evidence map›Paper›PMID 20664018›Full record

ArticleDiabetes care2010

Racial differences in the association between sex hormone-binding globulin and adiposity in premenopausal women: the BioCycle study.

Edwina H Yeung, Cuilin Zhang, Mary L Hediger, Jean Wactawski-Wende, Enrique F Schisterman

Open access · hybridAbstract read
In one paragraph

Article in Diabetes care, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Body Composition and Biological Functioning in Polish Perimenopausal Women with Type 2 Diabetes.International journal of environmental research and public health · 2021
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Edwina H YeungEpidemiology Branch, Division of Epidemiology, Statistics, and Prevention Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.
Cuilin Zhang
Mary L Hediger
Jean Wactawski-Wende
Enrique F Schisterman
Eunice Kennedy Shriver National Institute of Child Health and Human Development · USNational Institutes of Health · USUniversity at Buffalo, State University of New York · US

Funding

Oxidative Stress, Hormones and Women s HealthZIAHD008762 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI PERKINS, NEIL · 2009 to 2025
$3.1M
Intramural NIH HHS
6 · The paper itself

Abstract

objectiveTo assess the associations between measures of adiposity and sex hormone- binding globulin (SHBG) and to evaluate whether such associations differ by race. RESEARCH DESIGN AND

methodsAdiposity was measured by anthropometry and dual-energy X-ray absorptiometry among women (146 white, 50 black, and 25 Asian) aged 18-44 years in the BioCycle study. SHBG was repeatedly measured over one to two menstrual cycles. The ratio of trunkal to leg fat (T/L) was used to assess upper to lower body adiposity.

resultsAmong whites, all adiposity measures were significantly and inversely associated with SHBG. Among blacks, BMI (β = -0.032), waist circumference (β = -0.016), and T/L (β = -0.033) were significantly associated with SHBG, whereas total and trunkal fat were not (P interaction with race <0.04). Among Asians, measures of central and upper body fat were significantly associated with SHBG (e.g., T/L, β = -0.84) but not BMI.

conclusionsAssociations between SHBG and adiposity differ by race among premenopausal women.

Indexed as

Absorptiometry, PhotonAdiposityAdultBlack PeopleBody Mass IndexFemaleHumansPremenopauseSex Hormone-Binding GlobulinWhite PeopleYoung AdultSex Hormone-Binding Globulin

Identifiers

PMID20664018
PMCPMC2945174
OpenAlexW1972049088

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.