Trial reportEnvironmental health perspectives2010
Respiratory health effects of exposure to low-NOx unflued gas heaters in the classroom: a double-blind, cluster-randomized, crossover study.
Trial report in Environmental health perspectives, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 49 citations in OpenAlex.
- Volatile organic compounds and risk of asthma and allergy: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2015Pooled it
- Home interventions are effective at decreasing indoor nitrogen dioxide concentrations.Indoor air · 2014Trial
- Immune-mediated disease caused by climate change-associated environmental hazards: mitigation and adaptation.Frontiers in science · 2024Article
- Characterization of Indoor Air Quality on a College Campus: A Pilot Study.International journal of environmental research and public health · 2019Article
- 24-h Nitrogen dioxide concentration is associated with cooking behaviors and an increase in rescue medication use in children with asthma.Environmental research · 2017Article
- Seasonal variation of indoor and outdoor air quality of nitrogen dioxide in homes with gas and electric stoves.Environmental science and pollution research international · 2016Article
- Rhinoviruses significantly affect day-to-day respiratory symptoms of children with asthma.The Journal of allergy and clinical immunology · 2015Article
- A cross sectional analysis of behaviors related to operating gas stoves and pneumonia in U.S. children under the age of 5.BMC public health · 2015Article
- The indoor environment and inner-city childhood asthma.Asian Pacific journal of allergy and immunology · 2014Review
- Promotion of lung health: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.Annals of the American Thoracic Society · 2014Review
- Environmental remediation in the treatment of allergy and asthma: latest updates.Current allergy and asthma reports · 2014Review
- Recent trend in risk assessment of formaldehyde exposures from indoor air.Archives of toxicology · 2013Review
- Pediatric asthma: natural history, assessment, and treatment.The Mount Sinai journal of medicine, New YorkReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere are long-standing concerns about adverse effects of gas appliances on respiratory health. However, the potential adverse effect of low-NOx (nitrogen oxide) unflued gas heaters on children's health has not been assessed.
objectivesOur goal was to compare the respiratory health effects and air quality consequences of exposure to low-NOx unflued gas heaters with exposure to non-indoor-air-emitting flued gas heaters in school classrooms.
methodsWe conducted a double-blind, cluster-randomized, crossover study in 400 primary school students attending 22 schools in New South Wales, Australia. Children measured their lung function and recorded symptoms and medication use twice daily. Nitrogen dioxide (NO2) and formaldehyde concentrations were measured in classrooms using passive diffusion badges.
resultsNO2 concentrations were, on average, 1.8 times higher [95% confidence interval (CI), 1.6-2.1] and formaldehyde concentrations were, on average, 9.4 ppb higher (95% CI, 5.7-13.1) during exposure to unflued gas versus flued gas heaters. Exposure to the unflued gas heaters was associated with increased cough reported in the evening [odds ratio (OR) = 1.16; 95% CI, 1.01-1.34] and wheeze reported in the morning (OR = 1.38; 95% CI, 1.04-1.83). The association with wheeze was greater in atopic subjects. There was no evidence of an adverse effect on lung function.
conclusionsWe conclude that classroom exposure to low-NOx unflued gas heaters causes increased respiratory symptoms, particularly in atopic children, but is not associated with significant decrements in lung function. It is important to seek alternative sources of heating that do not have adverse effects on health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.