Evidence map›Paper›PMID 20663474›Full record

ArticleVeterinary research

Identification of a G2-like porcine rotavirus bearing a novel VP4 type, P[32].

Patrick J Collins, Vito Martella, Canio Buonavoglia, Helen O'Shea

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Article in Veterinary research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  19. Rotavirus infection: a perspective on epidemiology, genomic diversity and vaccine strategies.Indian journal of virology : an official organ of Indian Virological Society · 2011
    Article
  20. Analysis of human P[4]G2 rotavirus strains isolated in Brazil reveals codon usage bias and strong compositional constraints.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Patrick J CollinsDepartment of Biological Sciences, Cork Institute of Technology, Rossa Avenue, Bishopstown, Cork, Ireland.
Vito Martella
Canio Buonavoglia
Helen O'Shea

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A porcine group A rotavirus (GARV) strain, 61/07/Ire, was isolated from a 4-5 week asymptomatic piglet, during an epidemiological survey of porcine herds in Southern Ireland, in 2007. The nucleotide (nt) and amino acid (aa) sequence of the full-length VP4 protein of the PoRV strain 61/07/Ire was determined. Based on the entire VP4 open reading frame (nt), strain 61/07/Ire displayed ≤76.5% identity to representatives of the established 31 P-types, a value far lower than the percentage identity cutoff value (80%) established by the Rotavirus Classification Working Group (RCWG) to define a novel P genotype. Strain 61/07/Ire revealed low aa identity, ranging from 57.1% to 83.6%, to the cognate sequences of representatives of the various P genotypes. The aa identity was lower in the VP8* trypsin-cleavage fragment of the VP4, which encompasses the VP4 hypervariable region, ranging from 36.9% to 75.3%. Sequence analyses of the VP7, VP6, and NSP4 genes revealed that the GARV strain 61/07/Ire possessed a G2-like VP7, an E9 NSP4 genotype and an I5 VP6 genotype. Altogether, these results indicate that the GARV strain 61/07/Ire should be considered as a prototype of a new VP4 genotype, P[32], and provide further evidence for the vast heterogeneity of group A rotaviruses.

Indexed as

AnimalsAntigens, ViralCapsid ProteinsGene Expression Regulation, ViralIrelandPhylogenyRotavirusRotavirus InfectionsSwineSwine DiseasesAntigens, ViralCapsid ProteinsVP4 protein, RotavirusVP6 protein, Rotavirus

Identifiers

PMID20663474
PMCPMC2939698

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.