Evidence map›Paper›PMID 20663126›Full record

ArticleBMC microbiology2010

Molecular diversity of Mycobacterium tuberculosis isolates from patients with pulmonary tuberculosis in Mozambique.

Sofia O Viegas, Adelina Machado, Ramona Groenheit, Solomon Ghebremichael, Alexandra Pennhag, Paula S Gudo, Zaina Cuna, Paolo Miotto, Véronique Hill, Tatiana Marrufo and 4 more

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 51 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Non-Mycobacteria Tuberculosis in Africa: A Literature Review.Ethiopian journal of health sciences · 2023
    Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Exploring the usefulness of molecular epidemiology of tuberculosis in Africa: a systematic review.International journal of molecular epidemiology and genetics · 2020
    Review
  12. Article
  13. Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2019
    Article
  14. Article
  15. Article
  16. Article
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  19. Molecular identification ofEuropean academic research · 2016
    Article
  20. Molecular typing of mycobacteria isolated from tuberculous lymphadenitis cases in Addis Ababa, Ethiopia.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 5 countries.

Sofia O ViegasFaculty of Veterinary, Eduardo Mondlane University, Maputo Mozambique. viegas_sofia@hotmail.com
Adelina Machado
Ramona Groenheit
Solomon Ghebremichael
Alexandra Pennhag
Paula S Gudo
Zaina Cuna
Paolo Miotto
Véronique Hill
Tatiana Marrufo
Daniela M Cirillo
Nalin Rastogi
Gunilla Källenius
Tuija Koivula
Eduardo Mondlane University · MZSwedish Institute · SEInstitut Pasteur de la Guadeloupe · GPKarolinska Institutet · SEMinistry of Health · MZSan Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMozambique is one of the countries with the highest burden of tuberculosis (TB) in Sub-Saharan Africa, and information on the predominant genotypes of Mycobacterium tuberculosis circulating in the country are important to better understand the epidemic. This study determined the predominant strain lineages that cause TB in Mozambique.

resultsA total of 445 M. tuberculosis isolates from seven different provinces of Mozambique were characterized by spoligotyping and resulting profiles were compared with the international spoligotyping database SITVIT2.The four most predominant lineages observed were: the Latin-American Mediterranean (LAM, n = 165 or 37%); the East African-Indian (EAI, n = 132 or 29.7%); an evolutionary recent but yet ill-defined T clade, (n = 52 or 11.6%); and the globally-emerging Beijing clone, (n = 31 or 7%). A high spoligotype diversity was found for the EAI, LAM and T lineages.

conclusionsThe TB epidemic in Mozambique is caused by a wide diversity of spoligotypes with predominance of LAM, EAI, T and Beijing lineages.

Indexed as

Genetic VariationAdolescentAdultFemaleHumansMiddle AgedMolecular Sequence DataMozambiqueMycobacterium tuberculosisTuberculosis, PulmonaryYoung Adult

Identifiers

PMID20663126
PMCPMC2914001
OpenAlexW2017025841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.